Results 41 to 50 of about 54,524 (183)

Click Bioconjugation of Aza‐BODIPY Fluorophores to LfcinB Peptides for Improved Biocompatibility

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Click bioconjugation attaches NIR aza‐BODIPY fluorophores to LfcinB‐derived anticancer peptides via CuAAC and thiol‐maleimide chemistry. Conjugates exhibit improved predicted solubility while retaining strong NIR absorption (703–730 nm). Peptide‐aza‐BODIPY conjugates induce apoptotic morphology in HeLa cancer cells.
A. Verónica Rodríguez‐Mayor   +6 more
wiley   +1 more source

Perkins, Patricio Agustín.“La relación filosófica entre Husserl y Avenarius en Problemas fundamentales de la fenomenología.”

open access: yesIdeas y Valores, 2016
Perkins, Patricio Agustín.“La rela-ción filosófica entre Husserl y Avenarius en Problemas fundamentales de la fenomenología.” Diánoia 59.72 (2014): 25-48.
Juan Diego Bogotá
doaj   +3 more sources

Tandem Synthesis and Photophysical Behavior of Pyrazolo[3,4‐h][1,6]naphthyridines: A Theoretical–Experimental Approach

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A tandem reaction of 5‐aroylpyrazolo[3,4‐b]pyridines with malononitrile and methanol to access pyrazolo[3,4‐h][1,6]naphthyridines was achieved in 60%–66% yield under microwave conditions. The tricyclic fluorophoric core bears groups of different stereoelectronic nature (i.e., alkyl, aryl, MeO, and CN), and thus their optoelectronic activity shows ...
Carlos Cifuentes   +3 more
wiley   +1 more source

Impacto de la simplificación tributaria en Bogotá, Colombia

open access: yesRevista Colombiana de Ciencias Administrativas, 2022
Este artículo presenta el resultado del impacto de la simplificación tributaria de los impuestos industria, comercio y predial en la ciudad de Bogotá, Colombia, lo cual ha determinado un cambio conceptual de la tributación local, respecto a que el ...
Germán Torres Torres
doaj   +1 more source

Phytochemistry, Chemotypic Diversity and Antimicrobial Potential of Essential Oils From Native Aromatic Plants of the Americas: A Systematic Review

open access: yesFlavour and Fragrance Journal, EarlyView.
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez   +2 more
wiley   +1 more source

From Physiology to Bioheat Simulation: A Data‐Driven Framework for Core Temperature Initialization

open access: yesHeat Transfer, EarlyView.
ABSTRACT Accurate initialization of core body temperature is a critical yet often overlooked component of bioheat transfer models, particularly when such models are applied to heterogeneous populations and real‐world environmental conditions. Conventional bioheat simulations typically rely on fixed or idealized core body temperature values derived from
David S. Rodríguez   +6 more
wiley   +1 more source

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Evidence to guide the treatment for patients with metastatic castration‐resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with tumor harboring HRR alterations, progressed on a prior androgen ...
Lorena Incorvaia   +35 more
wiley   +1 more source

La activación de la revocatoria de mandato en el ámbito municipal en Colombia. Lecciones del caso de Bogotá

open access: yesEstudios Políticos, 2016
Este artículo analiza los factores que permiten comprender por qué en algunoscasos la revocatoria de mandato en el ámbito municipal logra ser activada conéxito, mientras que en otros casos se intenta activar y fracasa.
Cristhian Uribe Mendoza
doaj  

Fertility counseling and preservation considerations in patients with gynecologic and non‐gynecologic BRCA and Lynch‐associated malignancies

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer   +20 more
wiley   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

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