Assessment of BoHV-4-based vector vaccine intranasally administered in a hamster challenge model of lung disease [PDF]
Frontiers in Immunology, 2023 IntroductionBovine herpesvirus 4 (BoHV-4) is a bovine Rhadinovirus not associated with a specific pathological lesion or disease and experimentally employed as a viral vector vaccine.
Seok-Chan Park +10 more
doaj +10 more sources
Gammaherpesvirus BoHV-4 infects bovine respiratory epithelial cells mainly at the basolateral side [PDF]
Veterinary Research, 2019 Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus that is widespread in cattle. However, only a few studies about the pathogenesis of BoHV-4 primary infection have been reported.
Bo Yang +5 more
doaj +14 more sources
Primary replication and invasion of the bovine gammaherpesvirus BoHV-4 in the genital mucosae [PDF]
Veterinary Research, 2017 Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus that is widespread in cattle. Ex vivo models with bovine genital tract mucosa explants were set up to study molecular/cellular BoHV-4-host interactions.
Bo Yang +6 more
doaj +10 more sources
BoHV-4-based vector delivering Ebola virus surface glycoprotein [PDF]
Journal of Translational Medicine, 2016 Background Ebola virus (EBOV) is a Category A pathogen that is a member of Filoviridae family that causes hemorrhagic fever in humans and non-human primates.
Alfonso Rosamilia +9 more
doaj +11 more sources
Characterization of BoHV-4 ORF45 [PDF]
Frontiers in Microbiology, 2023 Bovine herpesvirus 4 (BoHV-4) is a Gammaherpesvirus belonging to the Rhadinovirus genus. The bovine is BoHV-4's natural host, and the African buffalo is BoHV-4's natural reservoir.
Luca Russo +7 more
doaj +8 more sources
OvHV-2 Glycoprotein B Delivered by a Recombinant BoHV-4 Is Immunogenic and Induces Partial Protection against Sheep-Associated Malignant Catarrhal Fever in a Rabbit Model [PDF]
Vaccines, 2021 An efficacious vaccine for sheep-associated malignant catarrhal fever (SA-MCF) is important for the livestock industry. Research towards SA-MCF vaccine development is hindered by the absence of culture systems to propagate the causative agent, ovine ...
Smriti Shringi +7 more
doaj +6 more sources
In vivo image analysis of BoHV-4-based vector in mice. [PDF]
PLoS ONE, 2014 Due to its biological characteristics bovine herpesvirus 4 (BoHV-4) has been considered as an appropriate gene delivery vector. Its genomic clone, modified as a bacterial artificial chromosome (BAC), is better genetically manipulable and can be used as ...
Valentina Franceschi +7 more
doaj +7 more sources
Genetic variability of bovine herpesvirus type 4 (BoHV-4) field strains from Turkish cattle herds [PDF]
Veterinaria Italiana, 2021 Bovine herpesvirus type 4 (BoHV‑4) is a common virus in the world that is detected in clinically ill or in apparently healthy cattle. This study provides a molecular characterization of BoHV‑4 strains from 24 cattle some showing respiratory and/or ...
Seval Bilge Dağalp +4 more
doaj +8 more sources
BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge. [PDF]
PLoS Neglected Tropical Diseases, 2015 Monkeypox virus (MPXV) is the etiological agent of human (MPX). It is an emerging orthopoxvirus zoonosis in the tropical rain forest of Africa and is endemic in the Congo-basin and sporadic in West Africa; it remains a tropical neglected disease of ...
Valentina Franceschi +11 more
doaj +7 more sources
Molecular Characterization of the First Bovine Herpesvirus 4 (BoHV-4) Strains Isolated from In Vitro Bovine Embryos production in Argentina. [PDF]
PLoS ONE, 2015 Bovine herpesvirus 4 (BoHV-4) is increasingly considered as responsible for various problems of the reproductive tract. The virus infects mainly blood mononuclear cells and displays specific tropism for vascular endothelia, reproductive and fetal tissues.
Erika González Altamiranda +7 more
doaj +7 more sources