Results 11 to 20 of about 13,135,533 (186)

Development of a BoHV-4 viral vector expressing tgD of BoHV-1 and evaluation of its immunogenicity in mouse model. [PDF]

Braz J Microbiol, 2021
In recent years, Bovine herpesvirus 4 (BoHV-4) has emerged as an attractive gene delivery viral vector, mainly for vaccination purposes in the veterinary field.
Bilge-Dagalp S, Farzani TA, Dogan F, Akkutay Yoldar Z, Ozkul A, Alkan F, Donofrio G.   +6 more
europepmc   +2 more sources

Genomic analysis of bovine herpesvirus type 4 (BoHV-4) from Argentina: High genetic variability and novel phylogenetic groups [PDF]

Veterinary Microbiology, 2012
Bovine herpesvirus 4 (BoHV-4) is a γ-herpesvirus that has been isolated both from apparently healthy animals and from cattle with a variety of clinical signs, including post-partum endometritis and abortion.
Jones, Leandro Roberto, Leunda, M. R., Manrique, Julieta Marina, Odeón, Anselmo Carlos, Pereyra, Susana Beatriz, Pérez, Sandra Elizabeth, Verna, Andrea Elizabeth   +6 more
core   +5 more sources

Genome sequence and experimental infection of calves with bovine gammaherpesvirus 4 (BoHV-4) [PDF]

Archives of Virology, 2022
Abstract Bovine gammaherpesvirus 4 (BoHV-4) is ubiquitous in cattle worldwide and it has been detected in animals exhibiting broad clinical presentations. The virus has been detected in the United States since the 70’s, however, its clinical relevance remains unknown.
Fernando Bauermann, S. Falkenberg, M. Martins, R. Dassanayake, J. Neill, Julia E Ridpath, S. Silveira, M. Palmer, Alaine R. Buysse, A. Mohr, E. Flores, D. Diel   +11 more
semanticscholar   +3 more sources

Bovine Herpesvirus-4 Based Vaccine Provides Protective Immunity against Streptococcus suis Disease in a Rabbit Model [PDF]

Vaccines, 2023
Streptococcus suis (S. suis) is a bacterial pathogen of pigs that has a major animal health and economic impact on the pig industry. Bovine herpesvirus-4 (BoHV-4) is a new virus-based vaccine vector that has been used for the immunogenic delivery of ...
Nihua Dong, Hester Nichols, Qing Sun, Xiaojun Chen, Jiayang Zheng, Zhixin Guan, Hailong Zhang, Andrew Davison, Yvonne Wezel, Zongjie Li, Beibei Li, Ke Liu, Donghua Shao, Yafeng Qiu, Jianhe Sun, Xiangdong Li, Mathew Upton, Zhiyong Ma, Michael A. Jarvis, Jianchao Wei   +19 more
doaj   +5 more sources

Search for the genome of bovine herpesvirus types 1, 4 and 5 in bovine semen [PDF]

Open Veterinary Journal, 2013
Bovine herpesvirus type 1 (BoHV-1) causes respiratory and reproductive disorders in cattle. Recently, bovine herpesvirus type 5 (BoHV-5) and bovine herpesvirus type 4 (BoHV-4) have been identified to be associated with genital disease. In this study, the
P.E. Morán, P.A. Favier, M. Lomónaco, M.C. Catena, M.L. Chiapparrone, A.C. Odeón, A.E. Verna, S.E. Pérez   +7 more
doaj   +8 more sources

Whole Genome Sequencing of a Canadian Bovine Gammaherpesvirus 4 Strain and the Possible Link between the Viral Infection and Respiratory and Reproductive Clinical Manifestations in Dairy Cattle

Frontiers in Veterinary Science, 2017
Bovine gammaherpesvirus 4 (BoHV-4) is a herpesvirus widespread in cattle populations, and with no clear disease association. Its genome contains a long unique coding region (LUR) flanked by polyrepetitive DNA and 79 open reading frames (ORFs), with ...
Carl A. Gagnon, Carolina Kist Traesel, Nedzad Music, Jérôme Laroche, Nicolas Tison, Jean-Philippe Auger, Sanela Music, Chantale Provost, Christian Bellehumeur, Levon Abrahamyan, Susy Carman, Luc DesCôteaux, Steve J. Charette, Steve J. Charette, Steve J. Charette   +14 more
doaj   +4 more sources

A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle. [PDF]

PLoS ONE, 2019
Recombinant herpesvirus vaccine vectors offer distinct advantages in next-generation vaccine development, primarily due to the ability to establish persistent infections to provide sustainable antigen responses in the host. Recombinant bovine herpesvirus-
Laura B A Williams, Lindsay M Fry, David R Herndon, Valentina Franceschi, David A Schneider, Gaetano Donofrio, Donald P Knowles   +6 more
doaj   +2 more sources

Bovine Herpesvirus Type 4 (BoHV-4) Vector Delivering Nucleocapsid Protein of Crimean-Congo Hemorrhagic Fever Virus Induces Comparable Protective Immunity against Lethal Challenge in IFNα/β/γR-/- Mice Models. [PDF]

Viruses, 2019
Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of a tick-borne infection with a significant mortality rate of up to 40% in endemic areas, with evidence of geographical expansion.
Aligholipour Farzani T, Földes K, Hanifehnezhad A, Yener Ilce B, Bilge Dagalp S, Amirzadeh Khiabani N, Ergünay K, Alkan F, Karaoglu T, Bodur H, Ozkul A.   +10 more
europepmc   +2 more sources

Laboratory Findings Suggesting an Association Between BoHV‐4 and Bovine Abortions in Southern Belgium [PDF]

Transboundary and Emerging Diseases, 2017
Abortions cause heavy economic losses for the bovine sector. The use of a standardized panel of analyses covering a large spectrum of pathogens responsible of abortion in cattle allowed demonstrating the direct involvement of at least one pathogen in 57%
L. Delooz, G. Czaplicki, J. Houtain, F. Dal Pozzo, C. Saegerman   +4 more
semanticscholar   +4 more sources

Immunization With Bovine Herpesvirus-4-Based Vector Delivering PPRV-H Protein Protects Sheep From PPRV Challenge [PDF]

Frontiers in Immunology, 2021
The Morbillivirus peste des petits ruminants virus (PPRV) is the causal agent of a highly contagious disease that mostly affects sheep and goats and produces considerable losses in developing countries.
Daniel Rodríguez-Martín, José Manuel Rojas, Francesca Macchi, Valentina Franceschi, Luca Russo, Noemí Sevilla, Gaetano Donofrío, Verónica Martín   +7 more
doaj   +3 more sources