Mapping the sites of latency and reactivation by bovine herpesvirus 5 (BoHV-5) and a thymidine kinase-deleted BoHV-5 in lambs [PDF]
Pesquisa Veterinária Brasileira, 2013 A thymidine kinase (tk)-deleted bovine herpesvirus 5 (BoHV-5tkΔ) was previously shown to establish latent infection and reactivate - even poorly - in a sheep model (Cadore et al. 2013). As TK-negative alphaherpesviruses are unlike to reactivate in neural tissue, this study investigated the sites of latency and reactivation by this recombinant in lambs.
Cadore, Gustavo C. +4 more
openaire +6 more sources
Differential expression of cyclins mRNA in neural tissues of BoHV-1- and BoHV-5- infected cattle [PDF]
Microbial Pathogenesis, 2019 Abstract Introduction Bovine alphaherpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are closely related alphaherpesviruses. BoHV-5 causes non-suppurative meningoencephalitis in calves. BoHV-1 is associated with several syndromes and, occasionally, can cause encephalitis.
M.S. Marin +5 more
openaire +4 more sources
Glycoprotein D of Bovine Herpesvirus 5 (BoHV-5) Confers an Extended Host Range to BoHV-1 but Does Not Contribute to Invasion of the Brain [PDF]
Journal of Virology, 2010 ABSTRACT Bovine herpesvirus 1 (BoHV-1) and BoHV-5 are closely related pathogens of cattle, but only BoHV-5 is considered a neuropathogen. We engineered intertypic gD exchange mutants with BoHV-1 and BoHV-5 backbones in order to address their in vitro and in vivo host ranges, with ...
Gabev E. +8 more
openaire +8 more sources
Análise antigênica de Herpesvírus Bovino tipos 1 (BoHV-1) e 5 (BoHV-5) com anticorpos monoclonais [PDF]
Acta Scientiae Veterinariae, 2018 Os herpesvirus bovino tipo 1 (BoHV-1) e tipo 5 (BoHV-5) sao responsaveis por uma serie de patologias em bovinos. A diferenciacao entre tipos e subtipos desses virus e importante para a compreensao da epidemiologia das infeccoes associadas a eles, assim como para permitir a tomada de medidas de controle adequadas.
Caixeta, Suzana Pereira de Melo Borges
core +6 more sources
Detecção de herpesvírus bovino 5 (BoHV-5) em bovinos do Sudeste Brasileiro
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2002 This paper reports the detection of bovine herpesvirus type 5 (BoHV-5) by a specific nested PCR assay. Samples were collected from the central nervous system (CNS) of cattle from Minas Gerais and Sao Paulo States, Brazil. All animals died presenting neurological symptoms.
Gomes, L. I. +7 more
openaire +6 more sources
Análise da região carbox-terminal da glicoproteína C (gC) e sua utilização na diferenciação entre Herpesvírus Bovino Tipos 1 (BoHV-1) e 5 (BoHV-5) [PDF]
Acta Scientiae Veterinariae, 2018 Membros da familia Herpesviridae , subfamilia Alphaherpesvirinae , herpesvirus bovino tipos 1 (BoHV-1) e 5 (BoHV-5) tem sido associados a diferentes condicoes clinicas em bovinos. Assim, diferenciacao entre BoHV-1 e BoHV-5 e uma valiosa informacao objetivando um melhor entendimento da patogenia e epidemiologia ...
Esteves, Paulo Augusto
core +5 more sources
Serological Evidence of Bovine Herpesvirus 5 (BoHV-5) in Cattle at the Colombia's Eastern Plains
, 2014 Several diseases involve the nervous system of cattle, among which infections with Rabies Virus and Bovine Herpes Virus 5 (BoHV-5) are noteworthy. In order to detect seropositive animals to BoHV-5, 156 Brahman-Zebu bovines blood samples from Colombia's eastern plains were analyzed through seroneutralization assay; the area has a history of animals ...
Pedraza-Ordonez, Francisco +4 more
openaire +2 more sources
Inducing Antigen-Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4-Based Vector. [PDF]
ImmunologyBovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Di Lorenzo A +7 more
europepmc +2 more sources
Genetic Characterization and Molecular Docking of Flavonoid Compounds Against <i>Klebsiella pneumoniae</i> and Bovine Herpesvirus Type 1 (BoHV-1) Isolated From Clinical Dairy Cattle Cases. [PDF]
Int J MicrobiolKlebsiella pneumoniae and Bovine Herpesvirus Type 1 (BoHV‐1) are two significant pathogens of dairy cattle that cause debilitating diseases in the respiratory, reproductive, and mammary gland systems. Conventional antimicrobials have become less effective due to the emergence of antimicrobial‐resistant strains, and other molecules are needed for ...
Hamzah KJ +5 more
europepmc +2 more sources
Transfecção de DNA de BoHV-5 com fosfato de cálcio em diferentes tipos de cultivos celulares
Acta Scientiae Veterinariae, 2018 As condicoes para uma transfeccao eficaz pelo metodo de fosfato de calcio podem variar substancialmente. Neste estudo foi testado o tipo de cultivo celular mais apropriado para transfeccao de DNA de herpesvirus bovino tipo 5 (BoHV-5) por esta tecnica. Primeiramente foi avaliada a capacidade de multiplicacao do BoHV-5 em tres diferentes tipos de celulas.
Dornelles, Eduardo Bortoluzzi +3 more
openaire +5 more sources