Results 31 to 40 of about 12,222 (262)

Post-weld Heat Treatment and Groove Angles Affect the Mechanical Properties of T92/Super 304H Dissimilar Steel Weld Joints

High Temperature Materials and Processes, 2018
The microstructures and mechanical properties of dissimilar weld joints between T92 and Super 304H steels were investigated. Dissimilar weld joints with four groove angles were constructed using gas tungsten arc welding. The results showed that post-weld
Shuo Wang, Limin Wei, Yi Cheng, Shuping Tan   +3 more
doaj   +1 more source

Simple Model of Pellet Combustion in Retort Burner

Communications, 2015
Combustion of the solid fuel in the burner is an important issue when discussing the CFD simulation of combustion in automatic boiler. In the present work is employed a simplified method for modeling the fuel bed, which is based on mass and heat balances
Jozef Micieta, Jiri Hajek, Jozef Jandacka   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Suppression method of combustion driven oscillation for industrial boilers with multi fuel injection nozzle burner

Nihon Kikai Gakkai ronbunshu, 2019
The initiation mechanism and its reduction method for combustion driven oscillation of industrial boilers with a center firing gas burner have been investigated experimentally and numerically.
Toshikazu TSUMURA, Akira BABA, Toshihisa UEDA, Osamu KAWAGUCHI   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Influence of the Air-coal Ratio on Transient Characteristics of the Ultra-supercritical Power Unit during the Load Cycling Processes

Zhongguo dianli
In order to study the influence of the air-coal ratio on the peak regulating characteristics of a coal-fired unit during load cycling transients, a dynamic model of a double-reheat ultra-supercritical coal-fired power plant with 660MW was established ...
Yong ZHANG, Chaoqiang YIN, Yugang LIU, Bin ZHANG, Chunhong MO, Chaoyang WANG   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Simulation of condensation unit in ASPEN PLUS

Известия высших учебных заведений: Проблемы энергетики, 2020
The article discusses the scheme of deep utilization of the heat of flue gases. It has been established that in boiler units operating on natural gas, the only way to significantly improve the use of fuel is to deeply cool the combustion products to a ...
A. A. Mikhin, V. V. Sergeev
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source