Results 201 to 210 of about 112,170 (310)
Advanced Science, EarlyView.An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li +11 more
wiley +1 more source
Experimental Study of High-Pressure Oxy-Fired Direct Contact Steam Generation (HiPrOx-DCSG) with Steam-Assisted Gravity Drainage (SAGD) Produced Water. [PDF]
ACS OmegaWu L, Herage T, Asiri M, Clements B.
europepmc +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
Advanced Science, EarlyView.The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Process liquor carbonation and simulation on an industrial scale, harnessing exhaust gas from light diesel oil fired boilers in mining and ore processing plants. [PDF]
Sci RepSharma VK, Thamida SK, Reddy BNK.
europepmc +1 more source
Advanced Science, EarlyView.Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li +11 more
wiley +1 more source
Optimal Scheduling of Energy Systems for Gas-to-Methanol Processes Using Operating Zone Models and Entropy Weights. [PDF]
Entropy (Basel)Wang X, Wei M, Wang J, Yue Y.
europepmc +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Advanced Science, EarlyView.Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
The Influence of the Use of Pyrolysis Oil as a Binder on the Physicochemical Properties of Pellets. [PDF]
Materials (Basel)Romankiewicz B, Gaze B.
europepmc +1 more source
Advanced Science, EarlyView.The plant hormone jasmonate is perceived by COI1‐JAZ co‐receptors comprising a single F‐box protein COI1 and multiple JAZ repressors with overlapping functions, complicating genetic analysis. We present a reactive antagonist (RA) strategy that selectively promotes COI1 binding to a cysteine‐engineered JAZ variant while blocking wild‐type JAZs, enabling
Minoru Ueda +10 more
wiley +1 more source