Practical Microwave-Assisted Recirculated Flow Esterification at Atmospheric Pressure. [PDF]
Schindler J, Harján R, Keglevich G.
europepmc +1 more source
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Phase transition of melt-vapor in the magnesium-tin system and its technological application. [PDF]
Volodin V +6 more
europepmc +1 more source
O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu +10 more
wiley +1 more source
A comparative study on meat quality traits and metabolomic profiles of different duck breeds following water boiling. [PDF]
Fan Z +6 more
europepmc +1 more source
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
Proteomic analysis of the eating quality of humped cattle beef from Rikaze cattle under various cooking methods. [PDF]
Zheng H +6 more
europepmc +1 more source
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Dynamic monitoring of salicylic acid and vitamin B<sub>2</sub> during the apple boiling process based on fluorescence spectroscopy and machine learning. [PDF]
Xu H +10 more
europepmc +1 more source

