Results 31 to 40 of about 3,586 (258)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
MATEC Web of Conferences, 2017 The paper presents the experimental results of evaporation of distilled water and 10% aqueous salt solutions of NaCl and СaCl2 droplets under their free falling on a heated surface.
Feoktistov D.V. +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Adaptation of SUBCAL subchannel code for square-lattice rod bundles using PSBT benchmark
Acta Polytechnica CTU ProceedingsSubchannel analysis is a commonly used approach for simulating heat transfer and coolant flow in nuclear reactor cores. This paper presents the adaptation of the SUBCAL computational code, originally developed for reactors with a triangular lattice, to ...
Lucie Titzová +2 more
doaj +1 more source
Bio-Protocol, 2023 In the field of molecular genetics, DNA extraction protocols and kits are sample-specific and proprietary, preventing lateral distribution among similar facilities from different sectors to alleviate supply shortages during a crisis.
Stavroula Goudoudaki +5 more
doaj +1 more source
Criticality in the slowed-down boiling crisis at zero gravity [PDF]
Physical Review E, 2015 Boiling crisis is a transition between nucleate and film boiling. It occurs at a threshold value of the heat flux from the heater called CHF (critical heat flux). Usually, boiling crisis studies are hindered by the high CHF and short transition duration (below 1 ms).
Charignon, T +6 more
openaire +4 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Experimental investigation of film boiling on spheres using high-speed video
EPJ Web of Conferences, 2012 The experimental investigation of saturated Freon-113 film boiling on spheres with different diameters at atmospheric pressure under conditions of free convection is executed.
Fedoseenko Ivan, Agaltsov Andrey
doaj +1 more source