Results 131 to 140 of about 27,123 (264)

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

Investigation of Flow Boiling Heat Transfer Performance of Grooved Metal Foam (Ni, Cu) Evaporators. [PDF]

Micromachines (Basel)
Cao J, Li H, Nian X, Zhang C, Zhang Y, Guo C.   +5 more
europepmc   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Pool Boiling Heat Transfer Characteristics of Hydrophobically Modified TiO₂@Carbon Nanotube Composite Nanofluids. [PDF]

Nanomaterials (Basel)
Wu Y, Lang Z, Wu G, Yu Y, Yan P, Yang Y, Zhang Z.   +6 more
europepmc   +1 more source

Ultra‐Low Intensity Continuous Wave Laser Ablation Propulsion With Graphene‐Engineered Wood

Advanced Science, EarlyView.
Graphene delignified wood converts continuous wave laser energy into thrust. Laser propulsion experiments in vacuum reveal the lowest laser ablation threshold intensities and the greatest density‐normalized specific impulse in literature. The results highlight graphene delignified wood as a potential efficient, sustainable, strong, and lightweight ...
Afnan S. M. Elmubasher, Rami Elkaffas, Mohamed Hamid Salim, Basel Altawil, Chanaka Sandaruwan, Shanavas Shajahan, Ahsan Baidar Bakht, Irfan Hussain, Blaise L. Tardy, Sean S. M. Swei, Yarjan Abdul Samad   +10 more
wiley   +1 more source

Improved Thermo-Hydraulic Stability and Boiling Heat Transfer Through a Novel Three-Layer Microchannel Heat Sink with 3/4 Open-Ring Pin Fin Arrays. [PDF]

Materials (Basel)
Liu G, Ji C, Liu Z, Lund PD, Liu Y, Xu F, Zhang S, Wang C, Li D.   +8 more
europepmc   +1 more source

Experimental Investigation on Pool Boiling Heat Transfer Performance Using Tungsten Oxide WO₃ Nanomaterial-Based Water Nanofluids. [PDF]

Materials (Basel), 2020
Kamel MS, Lezsovits F.
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

An Experimental Investigation on the Flow Boiling Heat Transfer Performance of Nanofluid in 3D Printing Minichannel Heat Sinks: A Comparative Study. [PDF]

Nanomaterials (Basel)
Zhou J, Yin Z.
europepmc   +1 more source

Salt templated and graphene nanoplatelets draped copper (GNP-draped-Cu) composites for dramatic improvements in pool boiling heat transfer. [PDF]

Sci Rep, 2020
Rishi AM, Kandlikar SG, Gupta A.
europepmc   +1 more source