Results 231 to 240 of about 109,409 (294)
Study on the Formation Mechanism and Critical Criterion of Transformer Jet Fire under External Heat Source. [PDF]
Sun R+5 more
europepmc +1 more source
A CMTM6 Nanobody Overcomes EGFR‐TKI Resistance in Non‐Small Cell Lung Cancer
Overcoming EGFR‐TKI resistance remains a critical challenge in NSCLC treatment. This study identifies CMTM6 as a key regulator of EGFR stability and demonstrates that a novel anti‐CMTM6 nanobody disrupts the CMTM6‐EGFR interaction. Targeting CMTM6 restores EGFR degradation, suppresses tumor growth, and confers therapeutic benefit in both CDX and PDX ...
Lu Xia+18 more
wiley +1 more source
Selective Extraction of Aromatics from Slurry Oil with Subcritical Water. [PDF]
Zhou NX+6 more
europepmc +1 more source
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue+15 more
wiley +1 more source
Cold Consolidation of Waste Glass by Alkali Activation and Curing by Traditional and Microwave Heating. [PDF]
Carollo F+8 more
europepmc +1 more source
Germanium Nanocrystals Synthesized in High-Boiling-Point Organic Solvents
Natalia Zaitseva+4 more
openalex +2 more sources
Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang+9 more
wiley +1 more source
Effect of Boiling Time on the Color, Water, Protein Secondary Structure, and Volatile Compounds of Beef. [PDF]
You L, Zhang Y, Ma Y, Wang Y, Wei Z.
europepmc +1 more source
USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang+13 more
wiley +1 more source