Results 271 to 280 of about 685,927 (353)
NF2 is Essential for Human Endoderm Development
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong+5 more
wiley +1 more source
General Equation for Expressing the Physicochemical Properties of Aliphatic Alcohols. [PDF]
Deng Q, Cao CT, Cao C.
europepmc +1 more source
Film boiling heat transfer and minimum-heat-flux(MHF)-point condition in subcooled pool boiling.
Shigefumi Nishio+2 more
openalex +2 more sources
RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma
RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang+6 more
wiley +1 more source
Optimization of HIV drugs through MCDM technique Analytic Hierarchy Process(AHP). [PDF]
Farooq FB+3 more
europepmc +1 more source
Prediction of the latent heat of vaporization at normal boiling point by use of refractive index.
Daisuke Hoshino+2 more
openalex +2 more sources
Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen+9 more
wiley +1 more source
Homogeneous boiling over melting ice. [PDF]
Hagan T, Vasel-Be-Hagh A.
europepmc +1 more source
SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi+11 more
wiley +1 more source