Results 291 to 300 of about 5,581,967 (394)

Characterization of polar compounds in a true boiling point distillation system using electrospray ionization FT-ICR mass spectrometry

open access: yes, 2014
Guilherme P. Dalmaschio   +8 more
semanticscholar   +1 more source

Self‐Catalyzed Chemically Coalescing Liquid Metal Emulsions

open access: yesAdvanced Science, EarlyView.
A new type of liquid metal emulsion is developed that chemically activates and becomes electrically conductive under mild thermal stimulus. The activation mechanism occurs through a unique set of catalytic dehalogenation and chemical oxide etching reactions. These emulsions are 3D printable and exhibit high shape retention after being heated.
Stephanie F. Zopf   +8 more
wiley   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

open access: yesAdvanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu   +19 more
wiley   +1 more source

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Peptidyl arginine deiminase 2 (PAD2) plays a key role in regulating macrophage function in Pseudomonas aeruginosa‐induced acute lung injury (ALI). Using single‐cell RNA sequencing and proteomics, a new PAD2‐catalyzed citrullination site on NF‐κB p65 (171 Arginine), modulating macrophage polarization is identified.
Xin Yu   +11 more
wiley   +1 more source

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