Results 121 to 130 of about 217,218 (308)

Functional Fibers in Soft Robotics: Advances in Material, Structural, and Systemic Tactics

Advanced Robotics Research, EarlyView.
Fiber‐form robotic systems offer a scalable pathway toward embodied intelligence in soft robotics. This review surveys functional fibers as material, structural, and systemic elements, highlighting advances in responsive materials, architectural programing, and fabrication strategies.
Joonhee Won, Jaehyun Jang, Hyeonseo Kim, Inyoung Choi, Steve Park, Seongjun Park   +5 more
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Gas–Liquid Two-Phase Boiling Heat Transfer Mechanism in Cooling Water Jacket of Intense Thermal Load Engine and Its Improvement

Applied Sciences
The results show that the numerical simulation error based on the RPI two-phase boiling heat transfer model is less than 5%, which is in good agreement with the test results.
Gangzhi Tang, Chaojie Yuan
doaj   +1 more source

Boiling in porous media: toward a local non-equilibrium model [PDF]

, 2014
Developing a macro-scale model describing accurately intense boiling in porous media, like in the case of the re-flooding of a debris bed reactor with strong solid heat source terms, is a real challenge. The existence of local non-equilibrium effects has
Duru, Paul, Fichot, Florian, Prat, Marc, Quintard, Michel, Sapin, Paul   +4 more
core  

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Two-phase flow characteristics and visualization of distributed confined array jet boiling

Case Studies in Thermal Engineering
Confined array jet boiling can achieve high heat flux in a compact space and its flow resistance characteristics are critical to the design of cooling systems.
Xinyu Ji, Xiaoping Yang, Xiang Ma, Hongmiao Tian, Jinjia Wei, Bengt Sunden   +5 more
doaj   +1 more source

Multiphase Flow Technology Impacts on Thermal Control Systems for Exploration [PDF]

The Two-Phase Flow Facility (TPHIFFy) Project focused on bridging the critical knowledge gap by developing and demonstrating critical multiphase fluid products for advanced life support, thermal management and power conversion systems that are required ...
Lekan, Jack, McQuillen, John, Sankovic, John   +2 more
core   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Development of a simplified boiling model applied for large-scale detailed two-phase flow simulations based on the VOF method

Mechanical Engineering Journal
The Japan Atomic Energy Agency (JAEA) is developing an evaluation method for a two-phase flow in the reactor core using simulation codes based on the volume of fluid (VOF) method.
Ayako ONO, Hiroto SAKASHITA, Susumu YAMASHITA, Takayuki SUZUKI, Hiroyuki YOSHIDA   +4 more
doaj   +1 more source