Results 101 to 110 of about 1,786,461 (344)
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingSemantic Change Detection (SCD) in remote sensing imagery requires models that integrate extensive spatial context for broad geographic patterns, computational efficiency for large-scale datasets, and sensitivity to class-imbalanced land-cover ...
Buddhi Wijenayake +6 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
低盐胁迫下
Haiyang yu huzhao大菱鲆是我国重要的养殖经济鱼类，随着养殖水域逐渐向滩涂和内陆拓展，亟待研究其低盐适应性机制，进而为培育耐低盐良种提供参考。通过腹腔注射干扰剂dsRNA以及激动剂T091317，以进一步检测下游脂质代谢相关基因的表达以及血清脂代谢产物的变化。研究设置两个盐度梯度(5和30)，每个盐度设置4个处理组(干扰组、激动组、生理盐水组和空白对照组)，实验周期72 h。结果显示：在dsRNA注射后，肝脏中LXRα基因的相对表达量呈现出显著的抑制作用，尤其是在盐度30下；盐度5的肝脏组以及不同盐度的肠道组中 ...
刘 志峰 +8 more
doaj +1 more source
Clinical, histological, and serological predictors of renal function loss in lupus nephritis.
Arthritis Care &Research, Accepted Article.Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Arthritis Care &Research, Accepted Article.Objective Individuals with SLE can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the area deprivation index (ADI), and FS in a national SLE sample. Methods Data were derived from RISE, a national electronic health record‐based registry.
Baljeet Rai +7 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi +4 more
wiley +1 more source