Results 161 to 170 of about 35,875 (259)

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

The Prostate, EarlyView.
ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi).
Lorena Incorvaia, Veronica Mollica, Ondřej Fiala, Kazutoshi Fujita, Yüksel Ürün, Bohuslav Melichar, Javier Molina‐Cerrillo, Teresa Alonso‐Gordoa, Umberto Basso, Maria T. Bourlon, Emmanuel Seront, Ugo De Giorgi, Maria José Juan Fita, Pasquale Rescigno, Tarek Taha, Fernando C. Maluf, Alexandr Poprach, Simona De Summa, Tomas Buchler, Luca Galli, Jindrich Kopecky, Gaetano Aurilio, Jakub Kucharz, Carlo Messina, Gabriel Berlingieri Polho, Sarah Scagliarini, Francesco Grillone, Diogo Assed Bastos, Luigi Formisano, Gian Paolo Spinelli, Alessandra Mosca, Alessandro Rizzo, Aristotelis Bamias, Fernando Sabino Marques Monteiro, Andrey Soares, Francesco Massari, Andrew J. Armstrong, Matteo Santoni   +37 more
wiley   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Development of a Novel Modular Footwear Setup for Testing the Isolated Biomechanical Effects of Footwear Features. [PDF]

J Foot Ankle Res
Sarlak H, Shakir K, Rogati G, Sartorato G, Leardini A, Berti L, Caravaggi P.   +6 more
europepmc   +1 more source

Benefits and Harms of Herbal Medicines for Preventing and Treating Acute Respiratory Infections: An Overview of Systematic Reviews

Phytotherapy Research, EarlyView.
Overview of systematic reviews evaluating the benefits and harms of herbal medicines for management of ARIs. ABSTRACT Hundreds of herbal medicines are currently marketed for the management of acute respiratory infections (ARIs). However, there is uncertainty about their benefits and harms, and clinical guidance remains unclear.
Fariba Aghajafari, Brian Choi, Devansh Bhatt, Susanna Maltoni, Elizabeth T. Thomas, Elena C. Rosca, Sara Gandini, Annette Plüddemann, Carl J. Heneghan, John M. Conly, Tom Jefferson, Igho J. Onakpoya   +11 more
wiley   +1 more source

TLR4: A Potential Therapeutic Target in the Experimental Pathogenesis of Hemolytic-Uremic Syndrome. [PDF]

Int J Mol Sci
Varrone E, Pepe V, Storci G, Bonafè M, Brunetti B, Brigotti M.   +5 more
europepmc   +1 more source

Coupled observation‐operator approximations in outer‐loop coupling data assimilation

Quarterly Journal of the Royal Meteorological Society, EarlyView.
We present a methodology for coupled variational data assimilation that allows the effect of coupled observation operators whilst maintaining separate minimisations across model components. This allows us to constrain the atmosphere, ocean, and sea‐ice components of our coupled model directly from satellite radiances. We illustrate the system in action
P. A. Browne, P. de Rosnay, A. J. Geer, S. Quesada‐Ruiz, T. Scanlon, E. Villeneuve   +5 more
wiley   +1 more source

Naphthalene-Based Aromatic Copolyesters Containing Polar Units with Improved Wettability and High Transparency for Biomedical Applications. [PDF]

Polymers (Basel)
Perrucci A, Pollutri D, Guidotti G, Soccio M, Versura P, Fontana L, Lotti N.   +6 more
europepmc   +1 more source

Enhancing severe convection forecasts with microwave radiance assimilation in limited‐area models

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Microwave satellite radiances remain largely underexploited in convection‐permitting limited‐area models. We assess the assimilation of humidity‐sensitive radiances from the MHS instrument in the operational ICON‐2I model, improving the precipitation forecast of a severe convective event over the Marche region, Italy, substantially by correcting ...
Marcello Grenzi, Thomas Gastaldo, Virginia Poli, Chiara Marsigli, Tijana Janjic, Alberto Carrassi   +5 more
wiley   +1 more source

Between utopias and everyday practices: ecopreneurs and new urban economies in Bologna. [PDF]

Front Sociol
Musmeci M, Sartori L.
europepmc   +1 more source