Results 231 to 240 of about 24,397 (302)

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng   +12 more
wiley   +1 more source

Adherence to the Mediterranean and Mediterranean‐Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diets and Parkinson's Disease Incidence in Women: Results from the Prospective E3N Cohort

open access: yesAnnals of Neurology, Volume 99, Issue 4, Page 1014-1029, April 2026.
Objective The evidence regarding adherence to dietary patterns and Parkinson's disease (PD) risk is inconsistent. Because of the long prodromal PD phase, reverse causation represents a major threat to investigations of diet in relation to PD. We examined whether adherence to the Mediterranean (MED) and Mediterranean‐Dietary Approaches to Stop ...
Mariem Hajji‐Louati   +6 more
wiley   +1 more source

Extracellular Vesicle‐Mediated Nucleolin Transfer in Glioblastoma: A Targetable Axis Driving Blood‐Tumour Barrier Formation

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
GBM‐derived EVs transfer NCL to endothelial cells to facilitate BTB formation. AS1411‐based PROTACs exploit NCL‐dependent transcytosis to selectively cross the BTB and enter GBM. By recruiting the NCL‐MDM2 complex, these PROTACs induce the targeted degradation of POIs (VEGFR2/EGFR) to suppress tumor growth.
Hongzhen Chen   +7 more
wiley   +1 more source

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