Results 131 to 140 of about 1,277,787 (315)

Bond Valuation: Price and Yield Analysis

open access: yes
reservedIn questo approfondimento verranno trattati nel dettaglio i principali aspetti teorici e applicativi che riguardano la valutazione dei bond. L'analisi si concentrerà sulla determinazione del prezzo, sia alla data di godimento della cedola che in
PRIANTE, FRANCESCA
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India's Bond Market-Developments and Challenges Ahead [PDF]

open access: yes
While India boasts a world-class equity market and increasingly important bank assets, its bond market has not kept up. The government bond market remains illiquid.
Schou-Zibell, Lotte, Wells, Stephen
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Model inversion of electrical engineering systems from bicausal bond graphs [PDF]

open access: yes, 2005
In this paper, the application of bicausal bond graphs for model inversion of typical electrical engineering systems is emphasised. Inverse models are particularly useful for the synthesis step of the system design process.
Sareni, Bruno   +2 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Bond as Notary Public for Charles Shoemaker

open access: yes
Bond for $500 dated September 13, 1864 of Charles F.Shoemaker, Mora County, New Mexico, as Notary Public for Mora County. Bond also signed by William R. Shoemaker and Joab Houghton, joint authors. Certified in Spanish by Pablo Valdes, Secretary or clerk,

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Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Bond for license

open access: yes
Bond for license to Robert Cary, Messervy and Webb to trade with the Utes. In the handwriting of James S. Calhoun, Superintendent of Indian Affairs, Santa Fe. Witnessed by Edward S. Davies.

core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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