Results 31 to 40 of about 1,405,072 (310)

Redefining myeloid cell subsets in murine spleen

open access: yesFrontiers in Immunology, 2016
Spleen is known to contain multiple dendritic and myeloid cell subsets, distinguishable on the basis of phenotype, function and anatomical location. As a result of recent intensive flow cytometric analyses, splenic DC subsets are now better characterized
Ying eHey   +3 more
doaj   +1 more source

Bond behavior of NSM strips in corroded/cracked reinforced concrete

open access: yesFrontiers in Built Environment, 2022
There is limited research on the bond behavior of NSM strips embedded in corroded/cracked reinforced concrete (RC). Therefore, this study was initiated to evaluate the bond behavior between corroded/cracked RC and NSM strips.
Nabil Al-Akhras, Osama Othman
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Grain-size distribution of starting sample of size class -3.35 mm: Reliability factor of the Bond work index of grindability [PDF]

open access: yesMining and Metallurgy Engineering Bor, 2013
The investigation of the Bond' work index of grindability of low-grade and high-grade copper ore from the Copper Mine Bor has given two, for the theory and practice of comminution processes, significant results.
Stanojlović Rodoljub   +2 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

A Comparison of Aerobic Fitness Testing on a Swim Bench and Treadmill in a Recreational Surfing Cohort: A Pilot Study

open access: yesSports, 2018
The intermittent manner of surfing accentuates the importance of both the aerobic and anaerobic energy systems. Currently, the optimal method of assessing surfing-specific aerobic fitness is using a swim bench (SWB) ergometer; however, their limited ...
Hamzeh Khundaqji   +5 more
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Physiological Indicators of Acute and Chronic Stress in Securely and Insecurely Attached Dogs Undergoing a Strange Situation Procedure (SSP): Preliminary Results

open access: yesVeterinary Sciences, 2022
The quality of the attachment bond towards the caregiver may affect the dog’s physiological responses to stressful stimuli. This study aimed to measure chronic and acute physiological parameters of stress in ten securely and ten insecurely attached dogs.
Giacomo Riggio   +4 more
doaj   +1 more source

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