Results 51 to 60 of about 4,369,569 (381)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Aquatic exercise and mental health: A scoping review

open access: yesComplementary Therapies in Medicine, 2022
Objectives: The aims of this review were to 1) summarise the breadth and types of research regarding the impact of aquatic exercise on mental health completed to date, 2) provide a clear indication of the intervention type, volume, measurement tools used,
Morgan Jackson   +3 more
doaj  

Bond Length - Bond Valence Relationships for Carbon - Carbon and Carbon - Oxygen Bonds [PDF]

open access: yes, 2015
In the present study, relationships are developed for determining bond orders (also referred to as bond valences or bond numbers) from published bond lengths for carbon-carbon (C-C) and carbon-oxygen (C-O) bonds.
Hardcastle, F. D., Harris, C.
core   +3 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

"Neon Gradient with palm trees" summer classes research help posters [PDF]

open access: yes, 2019
These posters were created to make BU students aware of BU Libraries' continued services throughout the summer ...
Bond, Greg
core  

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Quantitative Portfolio Management: Review and Outlook

open access: yesMathematics
This survey aims to provide insightful and objective perspectives on the research history of quantitative portfolio management strategies with suggestions for the future of research.
Michael Senescall, Rand Kwong Yew Low
doaj   +1 more source

Nurses, computers and pre-registration education [PDF]

open access: yes, 2009
Nursing informatics, the use of information and technology, to support the work of the nurse, is an essential part of the modern nurses’ job. In the UK this is supported by a range of National Health Service policy documents over the past decade ...
Bond, Carol S.
core   +1 more source

Regulation of protein-ligand binding affinity by hydrogen bond pairing

open access: yesScience Advances, 2016
Receptor-ligand H-bond pairings have evolved to promote high-affinity binding by reducing competitive interference with water. Hydrogen (H)-bonds potentiate diverse cellular functions by facilitating molecular interactions.
Deliang Chen   +5 more
semanticscholar   +1 more source

On the bond polytope

open access: yesAdvances in Geometry, 2023
Abstract While the maximum cut problem and its corresponding polytope has received a lot of attention inliterature, comparably little is known about the natural closely related variant maximum bond. Here, given a graph G = (V, E), we ask for a maximum cut δ(S) ⊆ E with S ⊆ V under the restriction that both G[S] as well as G[V \ S] are ...
Chimani, Markus   +2 more
openaire   +2 more sources

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