Results 41 to 50 of about 14,136 (264)
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Credit Rating Changes and the Bond Market – the Impact of Economic Development
The aim of the paper is to examine the impact of credit rating changes of a country on bond yields, taking into account this country’s level of economic development.
Patrycja Chodnica-Jaworska
doaj +1 more source
China’s official rates and bond yields [PDF]
Abstract Recent research shows that bond yields are influenced by monetary policy decisions. To learn how this works in a bond market that differs significantly from those in the US and Europe, we model Chinese bond yields using the one-year deposit interest rate as a state variable.
Fan, Longzhen, Johansson, Anders C.
openaire +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig +7 more
wiley +1 more source
This research aim to test return share difference between before, moment, and after bond rating announcement, test return share of company before experience across classes and after experience bond rating, test difference of company return share before ...
Rosyati Rosyati
doaj
Manajemen Laba, Profitabilitas, dan Likuiditas sebagai Peringkat Obligasi
The purpose of the study is to test the influence of earnings management, profitability, and liquidity to the bond rating. By purposive sampling method, we used 11 manufacturing companies that listed in the Indonesia Stock Exchange (IDX) during the 2013 ...
Ulya Anisa’ul Maghfiroh, - Fidiana
doaj
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Can the dual-rating regulation improve the rating quality of Chinese corporate bonds?
We developed a dual-reputational rating shopping model to introduce public and institutional reputations. Investor's and regulator's penalty rates are described as public and institutional reputations, respectively.
Xiangyun Zhou
doaj +1 more source
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu +7 more
wiley +1 more source

