Results 91 to 100 of about 246,187 (316)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Metal Bond Strength Regulation Enables Large-scale Synthesis of Intermetallic Nanocrystals for Practical Fuel Cells

, 2023
Structurally ordered L10-PtM (M = Fe, Co, Ni, etc) intermetallic nanocrystals (iNCs), benefiting from the chemically ordered structure and higher stability, are one of the best electrocatalysts used for PEMFC.
Qing, Li, Guoxiong, Wang, Xuan, Liu, Jiantao, Han, Jiashun, Liang, Shenzhou, Li, Shaojun, Guo, Yangyang, Wan, Junyi, Liu, Fan, Lv, Yingjun, Sun, Gang, Lu, Houfu, Lv, Jia, Xu, Siyang, Zhang, Zhi, Deng, Yunhui, Huang   +16 more
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Shear bond strength of precoated orthodontic brackets: an in vivo study

, 2010
Ali H HassanDepartment of Preventive Dental Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi ArabiaObjective: To evaluate the shear bond strength of precoated orthodontic brackets bonded with self-etching primer relative to that ...
Ali H Hassan
core  

Experimental research on bond behavior of high-strength reinforcement in unconfined fly ash-based geopolymer concrete

Case Studies in Construction Materials
Geopolymer concrete (GPC) has emerged as an eco-friendly ‌alternative‌ to ordinary Portland cement (OPC) concrete in ‌recent years‌, due to its ‌superior‌ mechanical properties and durability.
Jian Yuan, Jiayu Xiao, Deqiang Huang
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Optimisation of interfacial bond strength of glass fibre endodontic post systems.

, 2011
MPhilCurrently endodontically treated teeth are clinically restored using a post and crown system, where the elastic modulus of the post is similar to dentine.
Thanjal, Narinderjeet Tina
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Avaliação da resistência de união de braquetes ortodônticos colados com diferentes técnicas [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Nesta pesquisa laboratorial foi avaliada a resistência ao cisalhamento da união de braquetes de policarbonato, cimentados sobre o esmalte dentário com ...
Cé, Diogo Alencar
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