Results 81 to 90 of about 115,562 (259)

Macroeconomic Determinants of the Stock Market Index and Policy Implications: The Case of a Central European Country [PDF]

Eurasian Journal of Business and Economics, 2011
This paper examines the relationship between Hungary’s stock market index and relevant macroeconomic variables. The GARCH model is applied in empirical work.
Yu HSING
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Macroscopic and Microscopic Investigation on Microfractures in Blast-Conditioned Rock and the Influence of Particle Size

Applied Sciences
In the mining industry, particle size reduction is the most energy-demanding activity. Blasting represents the first stage of comminution. Experimental and field observations have demonstrated that blasting produces two main effects on rock: (i ...
Jacopo Seccatore, Sebastian Flores, Jose Oliden, Guillermo Pozo, Tatiane Marin   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Chemical analysis of Moringa oleifera (Moringaceae) seed oil and potentiation of antibiotic activity against standard and multidrug-resistant bacterial strains

Food Chemistry Advances
Moringa oleifera (“moringa”) seeds are sources of fixed oil with a composition of fatty acids important for their biological properties. This work aimed to verify the fixed oil of seed, regarding chemical composition, antibacterial activity alone and in ...
Erlânio Oliveira de Sousa, Anielle dos Santos Brito, Denise Magalhães Azevedo Feitoza, Aureliano de Albuquerque Ribeiro, Victória Hellen Nicácio Dias Tavares, Mayra Garcia Maia Costa, Crisiana de Andrade Nobre, Cícera Datiane de Morais Oliveira-Tintino, João Arthur de Oliveira Borges, Gildênia Alves de Araújo, Talysson Felismino Moura, João Paulo Martins de Lima, Sloana Giesta Lemos Florencio, Henrique Douglas Melo Coutinho, Irwin Rose Alencar de Menezes, Saulo Relison Tintino   +15 more
doaj   +1 more source

The innovative method for determining the approximate value of the Bond work index [PDF]

: In this study, we examine an innovative approach to determining the Bond work index, a key parameter in the mining and cement production industry that indicates material grindability. The method relies on the first-order kinetics law and allows for the estimation of approximate index values with any number of grinding cycles, depending on the desired
Todorović, Dejan, Ivošević, Branislav, Jovanović, Vladimir, Radulović, Dragan, Milošević, Vladan, Pavlović, Marko, Milićević, Sonja, Terzić, Anja   +7 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source