Results 41 to 50 of about 1,409 (258)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

In vitro Evaluation of Various Retention Protocols in Sustaining Treatment Outcomes Following Orthodontic Therapy

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Orthodontic therapy aims at achieving stable treatment outcomes by ensuring retention of corrected tooth positions. Various retention protocols have been proposed, but their efficacy in sustaining treatment outcomes remains unclear. Materials
Asha A. Hegde   +5 more
doaj   +1 more source

A survey of retention practices and protocols followed among orthodontists in India

open access: yesJournal of Pharmacy and Bioallied Sciences, 2021
Background: There are different types of retention protocols and retainers prescribed by the orthodontists across the globe. Aim: The study was conducted with the aim of evaluating the retention practices followed by the orthodontists in India. Materials
S R Radha   +5 more
doaj   +1 more source

Bonded lingual retainer adhesives and discoloration

open access: yesJournal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie, 2023
Abstract Purpose This in vitro study was conducted to compare the discoloration of a flowable self-adhesive composite, a highly filled composite adhesive, and a liquid polish applied highly filled composite adhesive for bonded lingual retainers.
Sabahat Yazıcıoğlu, Hasan Karadeniz
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Comparative Evaluation of Durability and Hygiene Between Multistrand Round Dead Soft and 8-Braid Flat Dead Soft Stainless Steel Retainer Wire

open access: yesJournal of Indian Orthodontic Society
Aim and Objectives The present study aims at evaluation and comparison of durability and hygiene between 2 different lingual retainer wires bonded between premolar to premolar, that is, maxillary or mandibular arch in the same patient.
Nitu Gautam   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Comparison of Two Different Retention Techniques on Re-Opening of Extraction Space at Different Intervals During the Retention Phase in Fixed Orthodontic Patients [PDF]

open access: yesIranian Journal of Orthodontics, 2014
Background: After completion of orthodontic treatment, the retention phase is necessary for premolar teeth to preserve them in an ideal esthetic and functional relationship and to counteract the inherent tendency of teeth to return to their previous ...
Aydin Sohrabi   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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