Results 121 to 130 of about 972,346 (318)

The Market for Borrowing Corporate Bonds [PDF]

open access: yes
This paper describes the market for borrowing corporate bonds using a comprehensive dataset from a major lender. The cost of borrowing corporate bonds is comparable to the cost of borrowing stock, between 10 and 20 basis points per year.
Thomas R. Covert   +3 more
core  

Indian War Bonds [PDF]

open access: yes, 1881
46-3Indian AffairsIndian War Bonds.
Senate Report No. 878, 46th Congress, 3rd Session (1881)
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Optimal Design of Weather Bonds

open access: yes
Replaced with revised version of paper 06/17/08.weather risk, weather bonds, reinsurance, securitisation, Agricultural Finance, Risk and Uncertainty,
Odening, Martin   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Possibilities of further emerging bond market development

open access: yesActa Economica, 2013
Since developed bond market is very important, it is indisputable that large force need to be directed to it’s further development in developing countries.
Нермина Побрић
doaj  

Guide to the Cheryl A. Wall Collection of Margaret Bonds and Florence Price Manuscript Scores

open access: yes, 2022
Cheryl A. Wall was a literary critic and English professor at Rutgers University who donated three manuscript scores to the CBMR – Troubled Water by Margaret Bonds with a handwritten autobiographical sketch by the composer on the back and two works by ...
Price, Florence, Bonds, Margaret
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sharing longevity risk: Why governments should issue longevity bonds

open access: yes
Government-issued longevity bonds would allow longevity risk to be shared efficiently and fairly between generations. In exchange for paying a longevity risk premium, the current generation of retirees can look to future generations to hedge their ...
Cairns, Andrew   +2 more
core  

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