Results 31 to 40 of about 972,346 (318)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Formation of Tawarruq Security Alternative to Bonds for Fiscal Policy [PDF]

open access: yesمطالعات مالی و بانکداری اسلامی, 2017
With regard to the prohibition of Riba in Islam, it is important to find an alternative to bonds that would be effective for financing the government deficit.
Seyed Mohsen Sajjadi, Mahdi Gholampoor
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Ambulatory Care Skills: Do Residents Feel Prepared?

open access: yesMedical Education Online, 2002
Objective: To determine resident comfort and skill in performing ambulatory care skills. Methods: Descriptive survey of common ambulatory care skills administered to internal medicine faculty and residents at one academic medical center.
Denise Bonds
doaj  

THE ANALYSIS OF ISSUE OF THE INDEXED BONDS IN THE RUSSIAN AND WORLD PRACTICE

open access: yesСтатистика и экономика, 2016
The article discusses the use of indexed bonds in a world practice, especially the issue of indexed bonds in Russia, analysis of their benefits for investors and issuers, investors and the analysis of potential results of the placement on the stock ...
Vladimir I. Kuznetsov   +1 more
doaj   +1 more source

POSITIVE EXPERIENCE IN SOLVING ECONOMIC PROBLEMS OF COMMERCIAL BANKS ON INVESTING IN BONDS

open access: yesВестник Северо-Кавказского федерального университета, 2022
BANKS ON INVESTING IN BONDS The banking system in the course of its activity acts as a complex dynamically developing system subject to a variety of different risks affecting the final results of the activities of a credit institution.
V. Bobrova, E. Zolotova, E. Kalashnikova
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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