Results 21 to 30 of about 2,335 (137)

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Craniofacial osseointegration of a large midfacial bone-anchored combination maxillofacial prosthesis: A clinical report

The Journal of Prosthetic Dentistry, 1996
The combination of retentive clips and magnets has been used with favorable results for smaller facial prostheses. This patient's large midfacial defect created the need for an attachment design that would retain an intraoral obturator prosthesis and a large silicone facial prosthesis.
J H, Evans, J W, Schweiger, R F, Wright
openaire   +2 more sources

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Pulsed electromagnetic field therapy on nonsurgical treatment of peri‐implantitis: 12–26 months follow‐up

Journal of Periodontology, EarlyView.
Abstract Background Pulsed electromagnetic field (PEMF) therapy, renowned for its immunomodulatory effects and established efficacy in orthopedics, shows promise for managing peri‐implantitis by reducing soft tissue inflammation and marginal bone loss.
Yaniv Mayer, Eran Gabay, Amin Younis, Ofir Ginesin, Rafael S. Siroma, Shlomo Barak, Ido Georgy, Yoni Friedlander, Thabet Asbi, Hadar Giladi Zigdon, Jamil A. Shibli   +10 more
wiley   +1 more source

Malleostapedotomy in Patients With Stapes Fixation: A Systematic Review

The Laryngoscope, EarlyView.
This systematic review analyses the current evidence on malleostapedotomy as a primary or revision procedure in patients with stapes fixation. Twenty‐five studies comprising 632 operated ears were included. Malleostapedotomy proved to be a safe and effective alternative to incus‐anchoring stapedoplasty, with favorable hearing outcomes and a low ...
Matteo Alicandri‐Ciufelli, Edoardo D'Alessandro, Daniela Lucidi, Riccardo Nocini, Hui Davide Qiu   +4 more
wiley   +1 more source

Interventions for the Diagnosis and Management of Otosclerosis: An Umbrella Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Perform an umbrella review (a systematic review of systematic reviews) to identify interventions for the prevention, diagnosis, and management of otosclerosis, to inform the development of the World Health Organization (WHO) Package of Ear and Hearing Care Interventions (PEHCI). Data Sources PubMed, Scopus, and Ovid MEDLINE databases
Isabelle J. Chau, Lauren R. McCray, Shaun A. Nguyen, Robert F. Labadie, Carolina Der, Lauren K. Dillard   +5 more
wiley   +1 more source

Retrieved bone-anchored percutaneous amputation prosthesis showing maintained osseointegration after 11 years—a case report

Acta Orthopaedica, 2014
The patient is a woman born in 1960. She suffered a high transfemoral amputation due to a tumor in 1976. In 1993, she was enrolled for treatment with a custom-designed bone-anchored implant solution. The surgery was performed in 2 stages, Briefly, at stage 1 of surgery (S1), a titanium fixture was implanted in residual femoral bone after reaming of the
Palmquist, Anders, Windahl, Sara H, Norlindh, Birgitta, Brånemark, Rickard, Thomsen, Peter   +4 more
openaire   +2 more sources

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Hydraulic and malleable female‐to‐male penile implants after phalloplasty in transgender individuals: a retrospective cohort analysis

BJU International, EarlyView.
Objectives To provide a comprehensive summary of the surgical outcomes of Zephyr Surgical Implants (ZSI; Geneva, Switzerland) hydraulic and malleable female‐to‐male (FTM) penile implants (PIs) in transgender patients. Patients and Methods All transgender patients who underwent hydraulic (ZSI FTM 475) and malleable (ZSI FTM 100) erectile device ...
Maya Levy, Wouter B. van der Sluis, Emma L. van Abbema, Brechje L. Ronkes, R. Jeroen A. van Moorselaar, Mark‐Bram Bouman, Garry L.S. Pigot   +6 more
wiley   +1 more source