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Bone and fat connection in aging bone
Current Opinion in Rheumatology, 2008The fat and bone connection plays an important role in the pathophysiology of age-related bone loss. This review will focus on the age-induced mechanisms regulating the predominant differentiation of mesenchymal stem cells into adipocytes. Additionally, bone marrow fat will be considered as a diagnostic and therapeutic approach to osteoporosis.There ...
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2000
There must be few fields of clinical medicine that are subject to as much confusion as osteoporosis. The diagnosis in any particular case is frequently uncertain, and may vary from specialist to specialist. There are no agreed investigation protocols, for diagnosing osteoporosis and the treatment tends to be arbitrary and stereotyped.
Nordin, B. +3 more
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There must be few fields of clinical medicine that are subject to as much confusion as osteoporosis. The diagnosis in any particular case is frequently uncertain, and may vary from specialist to specialist. There are no agreed investigation protocols, for diagnosing osteoporosis and the treatment tends to be arbitrary and stereotyped.
Nordin, B. +3 more
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2016
Osteoblasts derive from mesenchymal cells and produce osteoid, the organic matrix of bone, in two ways:
Christoph Bartl, Reiner Bartl
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Osteoblasts derive from mesenchymal cells and produce osteoid, the organic matrix of bone, in two ways:
Christoph Bartl, Reiner Bartl
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International Journal of Biomedical and Clinical Engineering, 2013
Bone age assessment defined as the measure of skeletal development is most often used in pediatrics and forensics to estimate the true age of a person. It is usually done by comparing the left hand X-ray of a person with the hand radiographs in the standard atlas or based on local regions of interests (ROI) that include epiphyseal regions of the ...
S. Kavya +5 more
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Bone age assessment defined as the measure of skeletal development is most often used in pediatrics and forensics to estimate the true age of a person. It is usually done by comparing the left hand X-ray of a person with the hand radiographs in the standard atlas or based on local regions of interests (ROI) that include epiphyseal regions of the ...
S. Kavya +5 more
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Ageing and bone structure [PDF]
, 1993 Ageing causes substantial changes in both the structure and the mechanical properties of bone, i.e. quantity and quality18,31. Bone loss throughout life has been observed in so many different populations, that it is regarded as a universal feature of ageing, also called ‘physiological osteopenia’6,31,44.
B. Frisch, R. Bartl
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Zhonghua yi xue za zhi, 2005
在骨质疏松的防治中,骨质量研究正引起人们的普遍兴趣和重视,此与骨密度(BMD)测量不能解释的许多临床现象有关,如应用氟剂治疗椎体BMD虽有很大改善,但却不能明显降低其骨折率;经抗骨折吸收的药物治疗,虽BMD面积改变不明显,但却能明显降低骨折率等.因此多方位地开展骨质量研究,会提高对骨质疏松诊疗水平,从骨组织衰老规律的角度来研究维护和改善骨质量有其重要意义。
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在骨质疏松的防治中,骨质量研究正引起人们的普遍兴趣和重视,此与骨密度(BMD)测量不能解释的许多临床现象有关,如应用氟剂治疗椎体BMD虽有很大改善,但却不能明显降低其骨折率;经抗骨折吸收的药物治疗,虽BMD面积改变不明显,但却能明显降低骨折率等.因此多方位地开展骨质量研究,会提高对骨质疏松诊疗水平,从骨组织衰老规律的角度来研究维护和改善骨质量有其重要意义。
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Novel approaches to target the microenvironment of bone metastasis
Nature Reviews Clinical Oncology, 2021Lorenz C Hofbauer +2 more
exaly