Results 91 to 100 of about 10,510,730 (248)
PSO for Graph-Based Segmentation of Wrist Bones in Bone Age Assessment
International Journal of Computers Communications & Control, 2012 Skeletal maturity is a reliable indicator of growth and skeletal bone age assessment (BAA) is used in the management and diagnosis of endocrine disorders. Bone age can be estimated from the left-hand wrist radiograph of the subject. The work presented in this paper proposes the development of an efficient technique for segmentation of hand-wrist ...
P. Thangam 0001 +2 more
openaire +2 more sources
Comparison of performance statistics of the ELM, ANN and GP bone age assessment models.
, 2015 Comparison of performance statistics of the ELM, ANN and GP bone age assessment models.
Iman Mazinani (799568) +4 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Bone Age Assessment in the Workup of Children with Endocrine Disorders
Hormone Research in Paediatrics, 2010 Bone age is a measure of developmental age, or physiological maturity, which represents more truthfully than chronological age, how far an individual has progressed towards full maturity. It is particularly helpful in the clinical workup of children with growth and/or puberty disorders as well as in treating decisions, such as whether to start ...
SPADONI, GIAN LUIGI, CIANFARANI, STEFANO
openaire +3 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Prevalent morphometric vertebral fractures in professional male rugby players. [PDF]
, 2014 There is an ongoing concern about the risk of injury to the spine in professional rugby players. The objective of this study was to investigate the prevalence of vertebral fracture using vertebral fracture assessment (VFA) dual energy X-ray ...
Beck, B. +14 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Journal of Orthopaedic Case ReportsIntroduction: Assessment of skeletal maturity is fundamental to pediatric orthopedic practice, as remaining growth potential influences prognosis and treatment decisions.
Shane Ross +5 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source