Results 141 to 150 of about 2,717,930 (384)

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

A freshwater diet-derived C-14 reservoir effect at the Stone Age sites in the Iron Gates gorge [PDF]

open access: yes, 2001
Human bones from single inhumation burials and artifacts made from terrestrial mammal (ungulate) bone found in direct association with the skeletons were obtained from the Stone Age site of Schela Cladovei situated just below the iron Gates Gorge of the ...
Bonsall, C.   +5 more
core  

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

open access: yesFEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti   +5 more
wiley   +1 more source

Strontium metabolism in the rebuilding of skeletal tissue [PDF]

open access: yes
The relationship between calcium and strontium in bone metabolism is described. Whole body comparisons in the form of balance studies, plasma kinetics, and biochemical bone differences are briefly reviewed. The value of strontium as a qualitative calcium

core   +1 more source

SARCOMA OF THE LONG BONES [PDF]

open access: green, 1907
WILLIAM B. COLEY
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Using Nonlinear Response to Estimate the Strength of an Elastic Network

open access: yes, 2001
Disordered networks of fragile elastic elements have been proposed as a model of inner porous regions of large bones [Gunaratne et.al., cond-mat/0009221, http://xyz.lanl.gov].
A. Hansen   +25 more
core   +2 more sources

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