The chondro-osseous continuum: is it possible to unlock the potential assigned within? [PDF]
Endochondral ossification (EO), by which long bones of the axial skeleton form, is a tightly regulated process involving chondrocyte maturation with successive stages of proliferation, maturation, and hypertrophy, accompanied by cartilage matrix ...
Adams+79 more
core +3 more sources
VEGF-C promotes the development of lymphatics in bone and bone loss
Patients with Gorham-Stout disease (GSD) have lymphatic vessels in their bones and their bones gradually disappear. Here, we report that mice that overexpress VEGF-C in bone exhibit a phenotype that resembles GSD.
Devon Hominick+9 more
doaj +1 more source
THE INFLUENCE OF AGE AND OF DURATION OF TREATMENT ON THE PRODUCTION AND REPAIR OF BONE LESIONS IN EXPERIMENTAL HYPERPARATHYROIDISM [PDF]
Henry L. Jaffe+2 more
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Induction of hemopoiesis in rat embryonic bone transplanted into adult subcutaneous connective tissue [PDF]
Five pairs of immature, non-hemopoietic femur and tibia from 17-day-old gestating female rat fetuses, whose sex was determined by chromosomal analysis of liver cells, were transplanted into subcutaneous tissues of adult male rats. The original bones were
Hsueh, Chao Liang
core +1 more source
The histology of the blood and the red bone‐marrow of the leopard frog, Rana pipiens [PDF]
H. E. Jordan
openalex +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
In vivo measurement of mechanical impedance of bone [PDF]
System of measurement provides indications of ulnar properties independent of characteristics of surrounding soft tissue and other bones. Mechanical modal approximated ulnar response so average bending rigidity could be determined to provide direct index
Thompson, G., Young, D. R.
core +1 more source
Osteoblastoma of the Os Capitatum
An osteoblastoma is a primary benign bone tumor, which is rarely seen in hand bones. Osteoblastoma is generally seen in spine, pelvis, and long bones. However, there are a few case reports of osteoblastoma in wrist and hand bones. To our knowledge, up to
Çağrı Kaptan, Halil Atmaca
doaj +1 more source
Background Limb bone lengths and bone mineral density (BMD) have been used to assess the bone growth and the risk of bone fractures in pigs, respectively. It has been suggested that limb bone lengths and BMD are under genetic control.
Ma Junwu+9 more
doaj +1 more source