Results 101 to 110 of about 1,982,048 (354)

Analysis of Femoral Components of Cemented Total Hip- Arthroplasty [PDF]

arXiv, 2014
In cemented Total Hip Arthroplasty (THA), material chosen for femoral stem and cross section of stem itself, proved to be critical parameters for, stress distribution in the femoral components, interfacial stresses and micro movements. Titanium alloy (Ti6Al4V), when used as a material for femoral stem, recorded large displacement as compared to ...
arxiv  

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang, Chao Yu, Mengyue Hu, Lu Wang, Meixia Chen, Hanmo Liu, Nan Wu, Jie Hou   +7 more
wiley   +1 more source

Laterally positioned flap with connective tissue graft to treat deep isolated gingival recessions in the mandibular anterior region: A retrospective case series with 10‐year follow‐up

Clinical Advances in Periodontics, EarlyView.
ABSTRACT Background To evaluate the efficacy and long‐term clinical outcomes of the one‐stage procedure for covering isolated deep gingival recessions (GRs) in the mandibular anterior region employing a laterally positioned flap (LPF) with a connective tissue graft (CTG), with a retrospective case series.
Lucrezia Parma‐Benfenati, Stefano Parma‐Benfenati   +1 more
wiley   +1 more source

Hyaluronic acid facilitates bone repair effects of calcium phosphate cement by accelerating osteogenic expression

Bioactive Materials, 2021
Calcium phosphate cements (CPC) are widely anticipated to be an optimum bone repair substitute due to its satisfied biocompatibility and degradability, suitable to be used in minimally invasive treatment of bone defects.
Xu Cui, Chengcheng Huang, Zhizhen Chen, Meng Zhang, Chunyu Liu, Kun Su, Jianyun Wang, Li Li, Renxian Wang, Bing Li, Dafu Chen, Changshun Ruan, Deping Wang, William W. Lu, Haobo Pan   +14 more
doaj  

Preparation and properties of α-tricalcium phosphate microspheres by spray drying [PDF]

Cerâmica
a-TCP microspheres were obtained by atomizing aqueous slurries containing 50 wt% of low crystallinity α-TCP and 1 wt% of citric acid. Poly(ethylene glycol) and poly(vinyl alcohol) were tested as a binder.
C. O. Renó, R. G. Carrodeguas, M. Motisuke, M. A. Rodríguez   +3 more
doaj   +2 more sources

Cardiac structural and molecular alterations in rodent models of temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Cardiac structural and molecular changes are prevalent in people with chronic epilepsy, possibly contributing to an increased risk of premature mortality. However, understanding of the underlying pathophysiological mechanisms is limited.
Zining Liu, Shobi Sivathamboo, Peravina Thergarajan, Flavia M. Gomes, Idrish Ali, Kim L. Powell, Piero Perucca, Nigel C. Jones, Terence J. O'Brien, Pablo Casillas‐Espinosa   +9 more
wiley   +1 more source

The addition of silicon nitride to PMMA bone cements reduces bacterial attachment while supporting preosteoblast viability

Next Materials
Injectable poly (methyl methacrylate) (PMMA) bone cements are widely used in orthopaedics to stabilize fractures and for implant fixation. However, bacterial attachment to bone cements leads to significant complications that can create a need for implant
Ioannis Katsaros, Estefanía Echeverri, Håkan Engqvist, Cecilia Persson, Wei Xia   +4 more
doaj  

Evaluation of the Effectiveness of Different Caries Removal Methods in Primary Teeth With Micro‐Computed Tomography and Scanning Electron Microscopy–Energy Dispersive Spectroscopy of X‐Ray

Microscopy Research and Technique, EarlyView.
The removal of the material effects was tested for its bone mineral density and Elemental analysis using SEM. ABSTRACT This study evaluated the effectiveness of conventional rotary instruments (CRI), atraumatic restorative treatment (ART), and the BRIX‐3000 chemomechanical caries removal gel by measuring bone mineral density (BMD) and mineral ...
Suna Nur Gokce, Arda Buyuksungur, Levent Ozer   +2 more
wiley   +1 more source

Biological and Mechanical Performance of Dual-Setting Brushite–Silica Gel Cements

Journal of Functional Biomaterials
Bone defects resulting from trauma, diseases, or surgical procedures pose significant challenges in the field of oral and maxillofacial surgery. The development of effective bone substitute materials that promote bone healing and regeneration is crucial ...
Valentin C. Steinacker, Tobias Renner, Ib Holzmeister, Sebastian Gubik, Urs Müller-Richter, Niko Breitenbücher, Andreas Fuchs, Anton Straub, Mario Scheurer, Alexander C. Kübler, Uwe Gbureck   +10 more
doaj   +1 more source

Automated Acetabular Defect Reconstruction and Analysis for Revision Total Hip Arthroplasty: A Computational Modeling Study

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Revision total hip arthroplasty (rTHA) involving large acetabular defects is associated with high early failure rates, primarily due to cup loosening. Most acetabular defect classification systems used in surgical planning are based on planar radiographs and do not encapsulate three‐dimensional geometry and morphology of the acetabular defect.
Daniel Hopkins, Stuart A. Callary, L. Bogdan Solomon, Peter V. S. Lee, David C. Ackland   +4 more
wiley   +1 more source