Results 201 to 210 of about 103,589 (360)

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Modified Sliding Fibular Graft for Aneurysmal Bone Cyst of the Lateral Malleolus: Technique and Two-Case Series. [PDF]

Foot Ankle Orthop
Marques de Oliveira F, Mateussi MV, Garcia JG, Petrilli MT, Viola DCM, Filho RJ.   +5 more
europepmc   +1 more source

Primary aneurysmal bone cyst of patella

, 2009
N. Somasekhar Reddy, VenkataReddy Sathi
openalex   +1 more source

Macrophage‐Targeted Magnesium Ion‐Nourisher for NLRP3 Inflammasome Inhibition to Enhance Liver Inflammatory Disease Treatment

Advanced Science, EarlyView.
This report describes a nano magnesium nourisher, named MgC@PS, capable of targeted Mg2⁺ delivery to macrophages, effectively suppressing The nuclear factor kappa B (NF‐κB) activation and mitigating NLRP3 inflammasome‐driven pyroptosis in liver inflammation.
Li Wang, Zhuo Yan, Sindhu Yalavarthi, Yusif Abdul‐Rashid, Kiki Parker, Kyle Nowlin, Ethan Li, Jordan Mack, Josephine Wei, Hunter Vu, Zhenquan Jia, Jianjun Wei, Jilong Wang, Kerui Wu   +13 more
wiley   +1 more source

Aggressive Aneurysmal Bone Cyst of the Mandible: A Rare Case of Rapid Expansion and Surgical Management. [PDF]

Clin Case Rep
Mashhadiabbas F, Gholami Toghchi S, Alehossein S, Norouzi H, Baher MK.   +4 more
europepmc   +1 more source

To fix or not to fix: A comparison of grafting with fixation versus grafting alone in proximal femur aneurysmal bone cysts

Ebubekir Eravşar, Ali Güleç, Selim Safalı, Ali Özdemir, Sadettin Çiftçi, Bahattin Kerem Aydın   +5 more
openalex   +2 more sources

Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine‐Driven Immune Suppression in Colorectal Cancer

Advanced Science, EarlyView.
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang, Renming Fan, Yongrui Hai, Ye Chen, Xintong Lu, Wenhui Wang, Jiarui Dou, Jiaxin Yan, Chang Su, Yue Chen, Le Yang, Minggao Zhao, Lei Liang, Gaofei Wei   +13 more
wiley   +1 more source

Gigantic lumbar aneurysmal bone cyst with abdominal extension in a pediatric patient: case report and its multidisciplinary management. [PDF]

J Spine Surg
Bourghli A, Konbaz F, Alsebayel F, Annaim M, Alyousif Z, Howsawi J, Habib Z, AlMusrea K.   +7 more
europepmc   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source