Results 31 to 40 of about 27,813 (209)

Denosumab in patients with aneurysmal bone cysts: A case series with preliminary results

Tumori, 2018
Purpose: Aneurysmal bone cyst (ABC) is a rare skeletal tumor usually treated with surgery/embolization. We hypothesized that owing to similarities with giant cell tumor of bone (GCTB), denosumab was active also in ABC.
E. Palmerini, P. Ruggieri, A. Angelini, S. Boriani, D. Campanacci, G. Milano, M. Cesari, A. Paioli, A. Longhi, M. Abate, G. Scoccianti, S. Terzi, G. Trovarelli, A. Franchi, P. Picci, S. Ferrari, M. P. Leopardi, M. Pierini   +17 more
semanticscholar   +1 more source

Bone: Aneurysmal bone cysts [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Aneurysmal bone cysts (ABC) are benign lesions that occur more frequently in the metaphyses of long bones, especially distal femur, the proximal tibia and vertebral posterior bodies. It can occur at any age but most patients are diagnosed in the first 2 decades of life.
openaire   +2 more sources

Unusual calvarial tumors

Journal of Medical and Scientific Research, 2015
Hypophosphatemic mesenchymal tumors of the skull bone otherwise known as oncogenic osteomalacia and aneurysmal bone cysts of the skull are rare tumors occurring in calvaria.
Manoranjitha Kumari, Manas Kumar, Krishna Reddy   +2 more
doaj   +1 more source

Dramatic response of aneurysmal bone cyst to denosumab: Case report and literature review

Clinical Case Reports, 2021
Denosumab, a monoclonal antibody that specifically targets cytokine receptor activator of nuclear factor‐kappa B ligand (RANKL), is a potentially viable option in resistant aneurysmal bone cysts.
Pedram Fadavi, Amir Mohammad Arefpour, Ramyar Hariri, Maryam Vasheghani, Maryam Garousi, Farzad Taghizadeh‐Hesary   +5 more
doaj   +1 more source

Surface Aneurysmal Bone Cyst

Journal of the Belgian Society of Radiology, 2015
We present a case of a surface aneurysmal bone cyst in a 19-year-old boy. Plain radiograph showed an osteolytic lesion with sclerotic margin and interrupted lamellar periosteal reaction at the posterolateral aspect of the diaphysis of the left proximal femur. MRI confirmed a bony lesion containing a fluid-fluid level (FFL) on T2-WI.
Jeoffrey De Roeck, Arn Van Royen, Filip Vanhoenacker   +2 more
openaire   +6 more sources

Greater wing of sphenoid, the home for aneurysmal bone cysts: a case report

Egyptian Journal of Neurosurgery, 2021
Background Finding an aneurysmal bone cyst in the skull is rare and for a neurosurgeon to come across such lesions in the sphenoid bone with orbital extension is even rarer.
Dibya Jyoti Mahakul, Prashant Sharma
doaj   +1 more source

Diagnosing and discriminating between primary and secondary aneurysmal bone cysts

Oncology Letters, 2017
Aneurysmal bone cysts (ABCs) are benign bony lesions frequently accompanied by multiple cystic lesions and aggressive bone destruction. They are relatively rare lesions, representing only 1% of bone tumors.
Hiromi Sasaki, S. Nagano, H. Shimada, M. Yokouchi, T. Setoguchi, Y. Ishidou, Osamu Kunigou, Kosuke Maehara, S. Komiya   +8 more
semanticscholar   +1 more source

Recurrent Aneurysmal Bone Cyst of the Distal Fibula Treated with Denosumab and Curettage

Case Reports in Oncological Medicine, 2018
We report the case of a 13-year-old girl with multiple recurrences of an aneurysmal bone cyst of the distal fibula successfully treated with denosumab and curettage. Aneurysmal bone cysts are locally aggressive lesions with high rates of recurrence.
Philip B. Fontenot, Jose Jesurajan, Marilyn Bui, Damon Reed, Odion Binitie   +4 more
doaj   +1 more source

Solid variant of aneurysmal bone cyst of the heel: a case report

Journal of Medical Case Reports, 2011
Introduction An aneurysmal bone cyst is a benign but often rapidly expanding osteolytic multi-cystic osseous lesion that occurs as a primary, secondary, intra-osseous, extra-osseous, solid or conventional lesion.
Stanc-Giannakopoulos Gabriela A, Gavresea Theofani V, Lekka Joanna A, Demertzis Nikolaos S   +3 more
doaj   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source