This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu +5 more
wiley +1 more source
Management of Humeral Solitary Bone Cysts in Children Using Elastic Stable Intramedullary Nailing-A Safe and Effective Minimally Invasive Treatment. [PDF]
Derzsi Z +9 more
europepmc +1 more source
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng +7 more
wiley +1 more source
Radiographic and histopathologic characteristics of simple bone cysts: a retrospective study of 46 cases. [PDF]
Tufan Yucesoy M +3 more
europepmc +1 more source
Porphyrin‐Based Porous Materials for Antibacterial Applications
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang +4 more
wiley +1 more source
Surgical Resection of Lumbar Spine Osteoblastoma With Secondary Aneurysmal Bone Cysts Through a Combined Transpsoas and Posterior Approach: A Case Report. [PDF]
Chen E +8 more
europepmc +1 more source
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao +5 more
wiley +1 more source
Two secondary aneurysmal bone cysts associated with mandibular fibrous dysplasia: a rare case and literature review. [PDF]
Louzada GP +5 more
europepmc +1 more source
A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation
ABSTRACT Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained largely unknown, in part ...
Marilou Tetard +7 more
wiley +1 more source
Subcortical Bone Cysts at the Medial Meniscus Posterior Root Are Associated with Longer Symptom Duration but Not with Healing Status or Meniscal Extrusion After Root Repair. [PDF]
Kim YM, Joo YB, Park YC.
europepmc +1 more source

