Results 241 to 250 of about 333,430 (360)

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Spatial Detection of Microsphere Polystyrene Plastics and Molecular Remodeling within a Full‐Body Mouse with MALDI Trapped Ion Mobility Mass Spectrometry Imaging

Angewandte Chemie, EarlyView.
Orally administered polystyrene microplastics accumulate in murine tissues and are detected using MALDI‐MSI with TIMS. Lipid profiling reveals decreases in hexosylceramides, sphingomyelins, and ether‐linked phospholipids, indicating altered metabolism.
Karina A. Vargas, Amy L. Parkhurst, Ming‐Fo Hsu, Christopher Hou, Fawaz G. Haj, Elizabeth K. Neumann   +5 more
wiley   +2 more sources

To fix or not to fix: A comparison of grafting with fixation versus grafting alone in proximal femur aneurysmal bone cysts. [PDF]

Jt Dis Relat Surg
Eravsar E, Güleç A, Safalı S, Özdemir A, Çiftci S, Aydin BK.   +5 more
europepmc   +1 more source

Aneurysmal Bone Cyst of the Dorsal Spine: Case Report

, 2020
S.-H. Touimi, S Daoudi, Imane Mbarki, I Adrif, H. Elkacemi, Sanaa Elmajjaoui, Tayeb Kebdani, H Errihani, N. Benjaafar   +8 more
openalex   +1 more source

Development of immunocompetent models for primary and metastatic ER+ breast cancer

Animal Models and Experimental Medicine, EarlyView.
This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull, Jody Hazlett, Emily Schulpen, Sophie Tunnicliffe, Alexander D. McLellan, Anita K. Dunbier   +5 more
wiley   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Modern treatment of unicameral and aneurysmatic bone cysts. [PDF]

EFORT Open Rev
Pala E, Trovarelli G, Angelini A, Cerchiaro MC, Ruggieri P.   +4 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Doxycycline Sclerotherapy of Mandibular Aneurysmal Bone Cysts: A Brief Clinical Study. [PDF]

J Craniofac Surg
Wong MN, Murakami JW.
europepmc   +1 more source

Unicameral bone cyst - femur

, 2010
Frank Gaillard
openalex   +1 more source