Results 31 to 40 of about 525,613 (267)

Measurement of bone density in osteoporosis [PDF]

open access: yesBMJ, 1995
EDITOR,--It is difficult to imagine a more wrong headed approach to osteoporosis than that proposed by E M Tayler.1 The first major misconception is that a bone density scan rarely influences a decision to start or continue hormone replacement therapy.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Tenofovir-associated bone density loss

open access: yesTherapeutics and Clinical Risk Management, 2009
Iwen F Grigsby1,2,3,4,5, Lan Pham1,2,4, Louis M Mansky3,4,5, Raj Gopalakrishnan3,4, Kim C Mansky1,2,41Division of Orthodontics, 2Department of Developmental and Surgical Sciences, 3Department of Diagnostic and Biological Sciences, 4MinnCResT Program ...
Iwen F Grigsby   +3 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Bone Mineral Density in Ankylosing Spondylitis

open access: yesTürk Osteoporoz Dergisi, 2003
Ankylosing Spondylitis (AS), a chronic inflammatory rheumatic disease. One of the most frequent and important complications in these patients is osteoporosis.
Bahar Çakmak, Hidayet Sarı
doaj  

Bone density and bone metabolism in plasmapheresis donors

open access: yesZhongguo shuxue zazhi
Objective To investigate the level of serum bone metabolism and biochemical markers and bone density of plasmapheresis donors, and to provide scientific basis for ensuring the health and safety of plasmapheresis donors in China.
Wan LI   +5 more
doaj   +1 more source

The Measurements of Maxillary Alveolar Bone Density at 13-15 Years Age by Using Spiral Computerized Tomography

open access: yesJournal of Baghdad College of Dentistry, 2016
Background: Bone density is a major factor that affect mini implant primarily stability; no Iraqi studies have evaluated bone density related to mini-implant placement for orthodontic anchorage at age 13 -15 years.
Azhar A Farage, Fakhri A Al Fatlawi
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bone Mineral Density in Stroke Patients

open access: yesTürk Osteoporoz Dergisi, 2005
Objective: Fractures after stroke are usually caused by the development of hemiosteoporosis and the high incidence of falls. The aim of this study was to compare bone mineral densities (BMDs) of paretic and nonparetic limbs in stroke patients and to ...
Nilüfer Balcı   +4 more
doaj  

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