Results 61 to 70 of about 5,756,169 (359)

Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density [PDF]

open access: hybrid, 2021
Daniel Schmitz   +5 more
openalex   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Relative Contribution of Trabecular and Cortical Bone to Primary Implant Stability: An In vitro Model Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Primary implant stability is a crucial factor for the successful osseointegration and long-term success of dental implants. The contribution of trabecular and cortical bone to primary implant stability is not well understood.
Trinanjali Bera   +7 more
doaj   +1 more source

Bone density and its importance in orthodontics

open access: yesJournal of Oral Biology and Craniofacial Research, 2013
Background: Researchers have generally focused on tissue reactions occurring within the periodontal ligament and bone to find possible explanation for various clinical phenomena, with less attention being paid to the inherent bone density.
Tina Chugh   +4 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Bone mineral density and body composition in girls with idiopathic central precocious puberty before and after treatment with a gonadotropin-releasing hormone agonist

open access: yesClinics, 2012
OBJECTIVES: Idiopathic central precocious puberty and its postponement with a (gonadotropin-releasing hormone) GnRH agonist are complex conditions, the final effects of which on bone mass are difficult to define. We evaluated bone mass, body composition,
Sandra B. Alessandri   +8 more
doaj   +1 more source

Bone Mechanical Properties in Healthy and Diseased States.

open access: yesAnnual Review of Biomedical Engineering, 2018
The mechanical properties of bone are fundamental to the ability of our skeletons to support movement and to provide protection to our vital organs.
E. Morgan   +2 more
semanticscholar   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Air pollution and decreased bone mineral density among Women's Health Initiative participants

open access: gold, 2023
Diddier Prada   +13 more
openalex   +1 more source

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