Results 101 to 110 of about 1,970,077 (362)

Use of percutaneous core needle biopsy for diagnosing acral bone tumors

Journal of Bone Oncology, 2017
This study aims to evaluate the diagnostic value of percutaneous core needle biopsy (PCNB) in diagnosing acral bone tumors. The clinical PCNB data of 341 patients with bone tumors were retrospectively analyzed.
Zhichao Tong, Mingyu Zhang, Bo Chen, Yujie Zhu, Jianfeng Wei, Xiaoju Li   +5 more
doaj   +1 more source

Temporary brittle bone disease:association with intracranial bleeding [PDF]

, 2013
We report 20 infants aged between 1 month and 6 months found to have subdural bleeding and also multiple unexplained fractures in a pattern similar to that described earlier as temporary brittle bone disease. Child abuse seemed unlikely as a cause of the
Ayoub, Ayoub, Bacopoulou, Bacopoulou, Barzegar, Barzegar, Caffey, Caffey, Dabezies, Dabezies, Evensen, Evensen, Fenton, Fenton, Gabaeff, Gabaeff, Galaznik, Galaznik, Garcia, Garcia, Geddes, Geddes, Gilman, Gilman, Gomez, Gomez, Graziani, Graziani, Gupta, Gupta, Hegedüs, Hegedüs, Jackson, Jackson, Jenny, Jenny, Keller, Keller, Kidd, Kidd, Kosmetatos, Kosmetatos, Lucas, Lucas, McLean, McLean, Mena, Mena, Mendelson, Mendelson, Miller, Miller, Muller, Muller, Nassogne, Nassogne, Ozdemir, Ozdemir, Parmar, Parmar, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Pontz, Pontz, Rooks, Rooks, Rorke, Rorke, Saarinen, Saarinen, Sasaki, Sasaki, Sayre, Sayre, Shearer, Shearer, Sillence, Sillence, Sohda, Sohda, Squier, Squier, Stanley, Stanley, Targher, Targher, Terling, Terling, Uscinski, Uscinski, Visser, Visser, Wei, Wei, Weir, Weir   +105 more
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Impacts of Prior Anti-Osteoporosis Treatments on Sequential Denosumab Responses in BMD Changes Among Postmenopausal Osteoporosis Women in East China: Real-World Data Analysis

Clinical Interventions in Aging
Guoyu Guan,1 Yanping Du,2,* Wenjing Tang,2 Minmin Chen,2 Weijia Yu,2 Huilin Li,2 Qun Cheng2,* 1Department of Geriatrics, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Osteoporosis and Bone ...
Guan G, Du Y, Tang W, Chen M, Yu W, Li H, Cheng Q   +6 more
doaj  

A rare incidence of severe dermatological toxicities triggered by concomitant administration of all-trans retinoic acid and triazole antifungal in patients with acute promyelocytic leukemia: a case series and review of the literature

Journal of Medical Case Reports
Background All-trans retinoic acid (ATRA) is an indispensable part of the treatment of acute promyelocytic leukemia (APL). Although, mild cutaneous toxicities like mucocutaneous xerosis, rash, and pruritus are well reported, ATRA associated severe ...
Aisha Jamal, Rafia Hassam, Qurratulain Rizvi, Ali Saleem, Anum Khalid, Nida Anwar   +5 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Research progress in the application of single‐cell sequencing technology in rheumatic diseases

Rheumatology & Autoimmunity
Rheumatic diseases, such as rheumatoid arthritis and systemic lupus erythematosus, represent a complex and heterogeneous group of immune‐mediated disorders.
Xinzhe Feng, Zhou Ji, Changhao Han, Zhi Li, Chenxu Liu, Weidong Xu   +5 more
doaj   +1 more source

Presenting signs and patient co-variables in Gaucher disease : outcome of the Gaucher Earlier Diagnosis Consensus (GED-C) Delphi initiative [PDF]

, 2019
© 2018 The Authors. Internal Medicine Journal by Wiley Publishing Asia Pty Ltd on behalf of Royal Australasian College of Physicians.Background: Gaucher disease (GD) presents with a range of signs and symptoms.
Belmatoug , N, Bembi , B, Bright, J, Deodato, F, Di Rocco, M, Goker-Alpan, O, Hughes, DA, Kuter, David, Lukina, EA, Machaczka, M, Mehta, Atul, Mengel, E, Nagral, A, Nakamura, K, Narita, A, Oliveri , B, Pastores, G, Pérez-López, J, Ramaswami, U, Salek, Mir-Saeed Shayegan, Schwartz, IV, Szer, J, Vom Dahl, S, Weinreb, NJ, Zimran, A   +24 more
core   +6 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Rheumatoid arthritis [PDF]

, 2016
Rheumatoid arthritis is a chronic inflammatory joint disease, which can cause cartilage and bone damage as well as disability. Early diagnosis is key to optimal therapeutic success, particularly in patients with well-characterised risk factors for poor ...
Aletaha, Daniel, McInnes, Iain B., Smolen, Josef S.   +2 more
core   +1 more source