Results 131 to 140 of about 1,970,077 (362)

Echocardiographic abnormalities and joint hypermobility in Chinese patients with Osteogenesis imperfecta

Orphanet Journal of Rare Diseases
Background Very little is known about the characteristics of echocardiographic abnormalities and joint hypermobility in Chinese patients with osteogenesis imperfecta (OI).
Yazhao Mei, Yunyi Jiang, Li Shen, Zheying Meng, Zhenlin Zhang, Hao Zhang   +5 more
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Transfer of the inflammatory disease of HLA-B27 transgenic rats by bone marrow engraftment. [PDF]

, 1993
Maxime Bréban, Robert E. Hammer, James A. Richardson, Joel D. Taurog   +3 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Clinical and genetic profiles of 985 Chinese families with skeletal dysplasia

Chinese Medical Journal, 2023
Shanshan Li, Shanshan Lyu, Wenzhen Fu, Yunqiu Hu, Hua Yue, Lin Chen, Zhenlin Zhang, Rongman Jia, Xiuyuan Hao   +8 more
doaj   +1 more source

Osteoporosis in Pregnant and Lactating Females: An Update

Türk Osteoporoz Dergisi
The purpose of writing this review is to provide an update on recent advances in pregnancy and lactation-associated osteoporosis (PLO) research and summarize the current evidence for specific treatments.
Nidhi Mishra, Hina Masroor, Madhu Gupta
doaj   +1 more source

Role of apoptosis in pathogenesis and treatment of bone-related diseases [PDF]

, 2015
Samaneh Mollazadeh, Bibi Sedigheh Fazly Bazzaz, Mohammad Amin Kerachian   +2 more
openalex   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Interventions for metabolic bone disease in children with chronic kidney disease [PDF]

, 2015
Deirdré Hahn, Elisabeth M Hodson, Jonathan C. Craig   +2 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source