Results 181 to 190 of about 12,182,524 (404)
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp+8 more
wiley +1 more source
T315I – a gatekeeper point mutation and its impact on the prognosis of chronic myeloid leukemia
BCR-ABL kinase domain mutations are an important cause of resistance to tyrosine kinase inhibitors (TKIs) in chronic myeloid leukaemia (CML) of which T315I is the most treatment-resilient. This study aimed to observe the frequency of T315I and its impact
Kaleem Bushra+2 more
doaj +1 more source
Objectives Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person‐centred care and informing local service pathways and care guidelines or standards.
Sonia Ranelli+8 more
wiley +1 more source
Impacto de la mutación T315I en el pronóstico de la leucemia mieloide crónica
Las mutaciones dominio quinasa BCR-ABL1 son una de las principales causas de resistencia a los inhibidores de la tirosina quinasa (ITK) en la leucemia mieloide crónica (LMC), siendo la mutación T315I la más resistente a tratamiento.
Kaleem Bushra+2 more
doaj +1 more source
Denosumab in patients with osteogenesis imperfecta and a historical control study with alendronate
PurposeOptimal dosing of denosumab in osteogenesis imperfecta (OI) remains undefined. This prospective cohort study evaluated the 12-month efficacy and safety of denosumab in OI patients, with a historical control study with alendronate.Materials and ...
Yazhao Mei+9 more
doaj +1 more source
Osteitis Deformans (Paget's Bone Disease) with Chronic Eczema
Fabian Weber
openalex +1 more source
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen+14 more
wiley +1 more source
Metastatic bone disease: Pathogenesis and therapeutic options
S. D’Oronzo+3 more
semanticscholar +1 more source
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard+15 more
wiley +1 more source
REMARKS ON THE MANAGEMENT OF SUPPURATION, COMPLICATING TUBERCULOUS DISEASE OF THE BONES AND JOINTS [PDF]
Henry Ling Taylor
openalex +1 more source