Results 31 to 40 of about 1,970,077 (362)

A virtual approach to evaluate therapies for management of multiple myeloma induced bone disease: Modelling Therapies for Multiple Myeloma Induced Bone Disease [PDF]

, 2015
Multiple myeloma bone disease is devastating for patients and a major cause of morbidity. The disease leads to bone destruction by inhibiting osteoblast activity while stimulating osteoclast activity.
Fagan, Michael J., Genever, Paul G., Ji, Bing   +2 more
core   +2 more sources

Sex differences in the prevalence and adverse outcomes of sarcopenia and sarcopenic obesity in community dwelling elderly in East China using the AWGS criteria

BMC Endocrine Disorders, 2019
Background Sarcopenia and sarcopenic obesity (SO) have a greater impact on the elderly. This study aimed to explore whether there were sex differences in the prevalence and adverse outcomes of sarcopenia and SO in community-dwelling elderly individuals ...
Yanping Du, Xiaodong Wang, Hua Xie, Songbai Zheng, Xiaoqing Wu, Xiaoying Zhu, Xuemei Zhang, Sihong Xue, Huilin Li, Wei Hong, Wenjing Tang, Minmin Chen, Qun Cheng, Jianqin Sun   +13 more
doaj   +1 more source

Synchrotron imaging assessment of bone quality [PDF]

, 2016
Bone is a complex hierarchical structure and its principal function is to resist mechanical forces and fracture. Bone strength depends not only on the quantity of bone tissue but also on the shape and hierarchical structure.
Abel, RL, Boughton, O, Cobb, JP, Hansen, U, Jin, A, Karunaratne, A, Ma, S   +6 more
core   +1 more source

Prevalence and Hospital Admissions in Patients With Osteogenesis Imperfecta in The Netherlands: A Nationwide Registry Study

Frontiers in Endocrinology, 2022
Osteogenesis Imperfecta (OI) is a complex disease caused by genetic alterations in production of collagen type I, and collagen-related proteins. Bone fragility is the most common patient issue, but extraskeletal complications also present an adverse ...
Silvia Storoni, Sanne Treurniet, Alessandra Maugeri, Gerard Pals, Joost G. van den Aardweg, Stéphanie L. van der Pas, Mariet W. Elting, Peter Kloen, Dimitra Micha, Elisabeth Marelise W. Eekhoff   +9 more
doaj   +1 more source

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats [PDF]

, 2019
Male Cy/+ rats have shown a relatively consistent pattern of progressive kidney disease development that displays multiple key features of late stage chronic kidney disease-mineral bone disorder (CKD-MBD), specifically the development of cortical bone ...
Allen, Matthew R., Chen, Neal X., Hill Gallant, Kathleen M., Lachcik, Pamela J., Metzger, Corinne E., Moe, Sharon M., Swallow, Elizabeth A., Vorland, Colby J.   +7 more
core   +1 more source

Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas. [PDF]

, 2020
BackgroundWhile racial/ethnic survival disparities have been described in pediatric oncology, the impact of income has not been extensively explored. We analyzed how public insurance influences 5-year overall survival (OS) in young patients with sarcomas.
Goldsby, Robert E, Murphy, Patricia, Penumarthy, Neela L, Shiboski, Stephen C, Winestone, Lena E, Wustrack, Rosanna   +5 more
core   +1 more source

Immunomagnetic t-lymphocyte depletion (ITLD) of rat bone marrow using OX-19 monoclonal antibody [PDF]

, 1989
Graft versus host disease (GVHD) may be abrogated and host survival prolonged by in vitro depletion of T lymphocytes from bone marrow (BM) prior to allotransplantation. Using a mouse anti-rat pan T-lymphocyte monoclonal antibody (0×19) bound to monosized,
A. Pascualone, A.L. Hoffman, B.F. Banner, Barclay A, Berenson R J, Beschorner W E, Bril H, D.G. Sheahan, D.V. Cramer, Dallman M J, Elkins W L, Farnsworth A, Filipovich A H, Kvalheim G, L. Makowka, Lubaroff D M, Martin P J, Monchik G J, Oaks M K, P. Rettinger, Prentice H G, Reisner Y, Rodt H, Slavin R E, T.E. Starzl, Thtschka P J, Tsoi M-S, Van Bekkum D W, Vartdal F, Waldman H, X. Cai   +30 more
core   +1 more source

Spotted bone disease [PDF]

BMJ Case Reports, 2015
Osteopoikilosis, a benign autosomal dominant bone disorder, is an unusual condition that can often be misdiagnosed as a sinister primary bone anomaly or as metastatic bony lesions. We report a case of osteopoikilosis in a 29-year-old Indian man. A 29-year-old unmarried man, born of non-consanguineous parents, presented with a history of low back pain ...
Riddhi, Dasgupta, Nihal, Thomas
openaire   +2 more sources

Muscle and bone characteristics of a Chinese family with spinal muscular atrophy, lower extremity predominant 1 (SMALED1) caused by a novel missense DYNC1H1 mutation

BMC Medical Genomics, 2023
Background Spinal muscular atrophy, lower extremity predominant (SMALED) is a type of non-5q spinal muscular atrophy characterised by weakness and atrophy of lower limb muscles without sensory abnormalities.
Yazhao Mei, Yunyi Jiang, Zhenlin Zhang, Hao Zhang   +3 more
doaj   +1 more source

Dynamics of Bone Trap-5b Level in Patients with Bone Metastases of Renal Cell Cancer at Combined Treatment [PDF]

, 2017
The objective of this study was to determine the sensitivity of tartrate-resistant acid phosphatase (Bone TRAP-5b) for early detection of bone metastases (BM) and to investigate the efficacy of bisphosphonates (BF) (zolendronic acid-ZA) in prevention of ...
Boichuk, S. (Serhiy), Diedkov, A. (Anatoliy), Kostiuk, V. (Viktor), Ostafiychuk, V. (Vasyliy)   +3 more
core   +2 more sources