Results 61 to 70 of about 12,182,524 (404)
International Journal of Endocrinology, 2013 The reference ranges of bone turnover markers (BTMs) were important during the treatment of osteoporosis, and the associations with bone mineral density (BMD) were controversial.
Wei-Wei Hu +8 more
doaj +1 more source
FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPKα-p38/MAPK pathway
Cell Communication and Signaling, 2023 Fibroblast growth factor 19 (FGF19) is recognized to play an essential role in cartilage development and physiology, and has emerged as a potential therapeutic target for skeletal metabolic diseases.
Shiyi Kan +11 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Identifying therapeutic biomarkers of zoledronic acid by metabolomics
Frontiers in Pharmacology, 2023 Zoledronic acid (ZOL) is a potent antiresorptive agent that increases bone mineral density (BMD) and reduces fracture risk in postmenopausal osteoporosis (PMOP). The anti-osteoporotic effect of ZOL is determined by annual BMD measurement.
Xiang Li +8 more
doaj +1 more source
A retrospective analysis of longitudinal changes in bone mineral content in cystic fibrosis [PDF]
, 2017 Background: We aimed to describe the longitudinal changes in bone mineral content and influencing factors, in children with cystic fibrosis (CF). Methods: One hundred children (50 females) had dual X-ray absorptiometry (DXA) performed.
Ahmed, Syed Faisal +7 more
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Adynamic bone disease--bone and beyond [PDF]
Clinical Kidney Journal, 2008 Disturbances of bone and mineral metabolism are a hallmark of chronic kidney disease (CKD). Renal osteodystrophy (ROD) is the traditional term for bone lesions in conjunction with CKD and is now considered a part of the ‘chronic kidney disease—mineral and bone disorder’ (CKD-MBD) [1].
Jürgen Floege, Vincent Brandenburg
openaire +3 more sources
A case of chronic recurrent multifocal osteomyelitis associated with Crohn's disease [PDF]
, 2015 Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-
De Baets, Frans +5 more
core
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Diagnosis and Treatment of Polycythemia Vera in Pakistan; Barriers and Possible Solutions [PDF]
Liaquat National Journal of Primary CareThis review aims to highlight the challenges encountered in managing Polycythemia Vera in resource-limited settings and to suggest a cost-effective strategy for timely diagnosis and treatment.
Rabab Jafry +4 more
doaj +1 more source