Results 71 to 80 of about 12,182,524 (404)
Change in hematologic indices over time in pediatric inflammatory bowel disease treated with azathioprine [PDF]
, 2010 Azathioprine leads to changes in mean corpuscular volume (MCV) and white blood cell (WBC) indices reflecting efficacy or toxicity. Understanding the interactions between bone marrow stem cells and azathioprine could highlight abnormal response patterns ...
A Timmer +18 more
core +2 more sources
Integrin αvβ3 Signaling in Tumor-Induced Bone Disease
Cancers, 2017 Tumor-induced bone disease is common among patients with advanced solid cancers, especially those with breast, prostate, and lung malignancies. The tendency of these cancers to metastasize to bone and induce bone destruction is, in part, due to ...
K. A. Kwakwa, J. Sterling
semanticscholar +1 more source
Bone Vasculature and Bone Marrow Vascular Niches in Health and Disease
Journal of Bone and Mineral Research, 2020 Bone vasculature and bone marrow vascular niches supply oxygen, nutrients, and secrete angiocrine factors required for the survival, maintenance, and self‐renewal of stem and progenitor cells.
Junyu Chen +4 more
semanticscholar +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
On Disease of the Mastoid Bone [PDF]
Journal of the Royal Society of Medicine, 1879 n ...
openaire +3 more sources
New England Journal of Medicine, 1993 Paget's disease of bone may present with bone pain but is often asymptomatic. Treatment (typically with bisphosphonates) is indicated in patients with pain that is localized to an affected site but not in asymptomatic patients.
openaire +8 more sources
Journal of Bone and Mineral Research, 2009 Bone disease is a characteristic feature of myeloma and causes devastating side effects that impact patient quality of life and survival. New findings over the last several years have led to a better understanding of the molecular mechanisms regulating bone disease including the understanding that myeloma bone disease results from hyperstimulation of ...
Ralph D. Sanderson, Joshua Epstein
openaire +2 more sources
Journal of Orthopaedic Surgery and Research, 2023 Background Circular RNAs (circRNAs) are important regulators on the onset and progression of rheumatoid arthritis (RA). Our purpose is to explore the role and underpin mechanism of circ_0000396 in RA progression.
Hongchao Yu +4 more
doaj +1 more source
A statistical method (cross-validation) for bone loss region detection after spaceflight. [PDF]
, 2010 Astronauts experience bone loss after the long spaceflight missions. Identifying specific regions that undergo the greatest losses (e.g. the proximal femur) could reveal information about the processes of bone loss in disuse and disease.
Chu, Philip W +7 more
core +3 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source