Results 121 to 130 of about 792,259 (266)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Clinical decision-making in rare bone diseases - A survey among members of the European Paediatric Orthopaedic Society (EPOS) and the European Reference Network on Rare Bone Diseases (ERN BOND). [PDF]

J Child Orthop
Gamage TH, Coutinho S, Leardini A, Alves I, Großmann N, Sakkers R, Marcucci G, Masi L, Brandi ML, Zillikens MC, Trisolino G, Wekre LL, Horn J.   +12 more
europepmc   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Capacity building of stem cell transplantation facilities in Pakistan: joint efforts of NIBD, government, and private-sector institutions

Blood Advances, 2019
Uzma Zaidi, Tahir S. Shamsi, Tasneem Farzana, Saqib H. Ansari, Munira Borhani, Saima Munzir, Shafaq Samad, Kousar Parveen, Nasreen Anjum, Irfan G. Mirza, Dilnasheen Safdar, Rida Naseem, Nasir A. Bukhari, Mansoor Mazari, Hira Jamil, Rukhsana Yousuf, Irfan A. Khan, Kamran Rasheed, Muhammad A. Mir   +18 more
doaj   +1 more source

Immune cell senescence and chronic bone diseases: osteoimmune mechanisms and therapeutic perspectives. [PDF]

Front Immunol
Wen Z, Yu M, Li S, Zeng F, Li J, Li J, Liang G, Wang K.   +7 more
europepmc   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Mammalian, plant, and gut microbiota-derived extracellular vesicles as emerging therapeutics for bone diseases. [PDF]

Front Bioeng Biotechnol
Yin G, Wang H, Liu Y, Wang Z, Lin X, Cheng Q, Gao H.   +6 more
europepmc   +1 more source

Paget disease of bone

Canadian Medical Association Journal, 2023
Pishdad, Reza, Moseley, Kendall F.
openaire   +2 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Bibliometric and visualized analysis of metal‒organic frameworks in bone tissue engineering and bone diseases. [PDF]

Discov Nano
Xia K, Yu L, Qin J, Zhu M, Fan M, Qian W.   +5 more
europepmc   +1 more source