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A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues +6 more
wiley +1 more source
Dental abnormalities in rare genetic bone diseases: Literature review. [PDF]
Iwata E +3 more
europepmc +1 more source
Prevalence of Common Metabolic Bone Diseases Diagnosed by Dual-Energy X-Ray Absorptiometry Scanning and Blood Test in Outpatients With Osteoarthritis the Knee. [PDF]
Chaiyavech N +2 more
europepmc +1 more source
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JAMA: The Journal of the American Medical Association, 1977
To the Editor.— The essay by Krishnamurthy et al (237:2504-2506, 1977) demonstrates the importance of total body imaging for detection of metastatic bone disease. The authors' findings also verify variations in routes of metastasis that depend on sites of the primary tumors.
N, Helman, A J, Helman
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To the Editor.— The essay by Krishnamurthy et al (237:2504-2506, 1977) demonstrates the importance of total body imaging for detection of metastatic bone disease. The authors' findings also verify variations in routes of metastasis that depend on sites of the primary tumors.
N, Helman, A J, Helman
openaire +4 more sources
Nursing Children and Young People, 2016
Brittle bone disease is also known as osteogenesis imperfecta, Vrolik syndrome and Lobstein syndrome. The condition is not gender specific and is present in all cultures. As the name of the disease suggests, the bones of people who have it are brittle and prone to fracture.
Doreen, Crawford, Annette, Dearmun
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Brittle bone disease is also known as osteogenesis imperfecta, Vrolik syndrome and Lobstein syndrome. The condition is not gender specific and is present in all cultures. As the name of the disease suggests, the bones of people who have it are brittle and prone to fracture.
Doreen, Crawford, Annette, Dearmun
openaire +2 more sources
Best Practice & Research Clinical Haematology, 2004
The major clinical manifestation of multiple myeloma is related to the osteolytic bone destruction. The bone disease can lead to pathologic fractures, spinal cord compression, hypercalcemia, and pain. It is also a major cause of morbidity and mortality in these patients.
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The major clinical manifestation of multiple myeloma is related to the osteolytic bone destruction. The bone disease can lead to pathologic fractures, spinal cord compression, hypercalcemia, and pain. It is also a major cause of morbidity and mortality in these patients.
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JAMA, 1961
THE VERY NAMES "disappearing bone disease" and "phantom bone" imply a lack of understanding of this rare and remarkable disease. It is noteworthy that the first case reported well over a century ago, without benefit of radiography or microscopy, remains as valid a description as any to date.
J M, ABELL, C E, BADGLEY
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THE VERY NAMES "disappearing bone disease" and "phantom bone" imply a lack of understanding of this rare and remarkable disease. It is noteworthy that the first case reported well over a century ago, without benefit of radiography or microscopy, remains as valid a description as any to date.
J M, ABELL, C E, BADGLEY
openaire +2 more sources

