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Wnt modulation in bone healing
Bone, 2020Genetic studies have been instrumental in the field of orthopaedics for finding tools to improve the standard management of fractures and delayed unions. The Wnt signaling pathway that is crucial for development and maintenance of many organs also has a very promising pathway for enhancement of bone regeneration.
Edward J. Harvey +4 more
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The Effect of Opiates on Bone Formation and Bone Healing
Current Osteoporosis Reports, 2020Opioids have been shown to be associated with an increased risk of fracture. The purpose of this paper is to review recent research into the effects of opioids on bone formation and bone healing in animal models and in human studies.Most opioids, such as morphine and fentanyl, negatively affected bone remodeling and bone healing in animal models ...
Maria Sole Scerpa +5 more
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Advanced Functional Materials, 2021
Bone bleeding and bone defects arising from trauma or bone tumor resection pose a great threat to patients and they are challenging problems to orthopedic surgeons.
Weijuan Huang +5 more
semanticscholar +1 more source
Bone bleeding and bone defects arising from trauma or bone tumor resection pose a great threat to patients and they are challenging problems to orthopedic surgeons.
Weijuan Huang +5 more
semanticscholar +1 more source
Bone Healing and Bone Substitutes
Facial Plastic Surgery, 2002With the advent of new biomaterials and surgical techniques, the reconstructive surgeon has a wider range of treatment modalities for the rehabilitation and reconstruction of craniofacial skeletal deformities than ever before. These innovative substances act as true bone graft substitutes, thereby allowing the surgeon to avoid the use of autogenous ...
Satish Govindaraj +3 more
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Expert Opinion on Investigational Drugs, 2012 The biological process of fracture healing is complex with influences that are both patient-dependent and related to the trauma experienced and stability of the fracture. Fracture healing complications negatively affect the patient's quality of life, even more when fractures occur in the elderly osteoporotic patients.In the polytherapy for bone ...
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Critical Reviews in Physical and Rehabilitation Medicine, 2000
Impaired bone healing has been a known problem since ancient times. Numerous methods have been tried during the medical history to solve this problem. Bone grafting has until recently been the main treatment of impaired bone healing. During the last two decades the rapid development of biotechnology and biomaterials have led to numerous new materials ...
Lind, Martin +5 more
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Impaired bone healing has been a known problem since ancient times. Numerous methods have been tried during the medical history to solve this problem. Bone grafting has until recently been the main treatment of impaired bone healing. During the last two decades the rapid development of biotechnology and biomaterials have led to numerous new materials ...
Lind, Martin +5 more
openaire +2 more sources
Nanotechnology and Bone Healing
Journal of Orthopaedic Trauma, 2010Nanotechnology and its attendant techniques have yet to make a significant impact on the science of bone healing. However, the potential benefits are immediately obvious with the result that hundreds of researchers and firms are performing the basic research needed to mature this nascent, yet soon to be fruitful niche.
Srikar Vengallatore +2 more
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Veterinary Clinics of North America: Small Animal Practice, 1999
Bone is composed of cells and organic matrix (30%), and minerals (70%). A vascular network consisting of nutrient, metaphyseal, and periosteal vessels richly supplies adult bone. Fracture healing consists of three interrelated phases: inflammatory, repair, and remodeling, and culminates in the ability of bone to return to original tissue structure ...
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Bone is composed of cells and organic matrix (30%), and minerals (70%). A vascular network consisting of nutrient, metaphyseal, and periosteal vessels richly supplies adult bone. Fracture healing consists of three interrelated phases: inflammatory, repair, and remodeling, and culminates in the ability of bone to return to original tissue structure ...
openaire +3 more sources
Orthobiologics for Bone Healing
Clinics in Sports Medicine, 2019Orthobiologics are a group of biological materials and substrates that promote bone, ligament, muscle, and tendon healing. These substances include bone autograft, bone allograft, demineralized bone matrix, bone graft substitutes, bone marrow aspirate concentrate, platelet-rich plasma, bone morphogenetic proteins, platelet-derived growth factor ...
Scott A. Rodeo, Jacob G. Calcei
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Clinics in Plastic Surgery, 1977
Secondary fracture healing with callus fomation involves the immediate reaction of this special kind of connective tissue (as well as others) with rapid increase in the reduplication of periosteal, paraosseal, and, to a lesser extent, endosteal cells. There is increased metabolism of glycosaminoglycan collagen synthesis, and transformation of fibrous ...
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Secondary fracture healing with callus fomation involves the immediate reaction of this special kind of connective tissue (as well as others) with rapid increase in the reduplication of periosteal, paraosseal, and, to a lesser extent, endosteal cells. There is increased metabolism of glycosaminoglycan collagen synthesis, and transformation of fibrous ...
openaire +2 more sources