Results 101 to 110 of about 369,836 (314)

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]

, 2017
Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu, Guillaume Mabilleau, Iepsen, Iepsen, Marie Pereira   +4 more
core   +5 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Occupations magdaléniennes entre 20 000 et 15 000 cal BP dans le piémont pyrénéen : la séquence paléolithique du sondage 4 de la grotte de Laa 2 (Arudy, Pyrénées-Atlantiques)

Gallia Préhistoire, 2017
Because of its rich record of Magdalenian sites, the Arudy Basin is a key case for the study of resettlement dynamics in the Pyrenean valleys after the Last Glacial Maximum.
Jean-Marc Pétillon, Véronique Laroulandie, Myriam Boudadi-Maligne, Patrice Dumontier, Catherine Ferrier, Delphine Kuntz, Mathieu Langlais, Jean-Baptiste Mallye, Vincent Mistrot, Christian Normand, Olivia Rivero Vilá, Marta Sánchez de la Torre   +11 more
doaj   +1 more source

Grotta Romanelli (Southern Italy, Apulia). Legacies and issues in excavating a key site for the Pleistocene of the Mediterranean [PDF]

, 2018
Grotta Romanelli, located on the Adriatic coast of southern Apulia (Italy), is considered a key site for the Mediterranean Pleistocene for its archaeological and palaeontological contents. The site, discovered in 1874, was re-evaluated only in 1900, when
Brilli, M, Giustini, F, Iurino, Da, Lembo, G, Massussi, M, Mazzini, I, Mecozzi, B, Muttillo, B, Sardella, R, Sigari, D, Tucci, S, Voltaggio, M   +11 more
core   +2 more sources

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Bio-engineered microRNA-7 effectively interferes with the Akt3/p53 axis to suppress human non-small cell lung cancer

Cancer Cell International
Non-small cell lung cancer (NSCLC) remains the leading cause of cancer deaths worldwide. Unfortunately, effective treatment is still lacking. The p53 tumor-suppressor protein is a critical mediator of cellular growth arrest and apoptosis, and is closely ...
Qian Huang, Xiaohua Chu, Chaofei Yang, Ying Huai, Chenyang He, Xingcong Ma, Jiawei Pei, Junhong Gao, Zhiyong Liu, Shanfeng Jiang, Airong Qian, Ye Tian   +11 more
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Taurine ameliorates lung injury induced by VOCs inhalation exposure in young rats

Journal of Functional Foods
Exposure to volatile organic compounds (VOCs) is associated with an increased risk of lung function impairment and inflammation, particularly in infants and children. However, there is still lack of effective protective methods.
Yongchao Gao, Zhiyong Liu, Xuan Xie, Ting Gao, Zhao Yang, Wangwang Guo, Airong Qian, Lifang Hu, Junhong Gao   +8 more
doaj   +1 more source

Soviet Illegal Whaling: The Devil and the Details [PDF]

, 2011
In 1948, the U.S.S.R. began a global campaign of illegal whaling that lasted for three decades and, together with the poorly managed “legal” whaling of other nations, seriously depleted whale populations.
Brownell, Jr. , Robert L., Clapham, Phillip J., Ivashchenko, Yulia V.   +2 more
core