Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su +8 more
wiley +1 more source
Unprecedented tibial bone lengthening of 33.5 cm by distraction osteogenesis for the reconstruction of a subtotal tibial bone defect. A case report and literature review. [PDF]
Ali A, Ren Y, Zhou CH, Fang J, Qin CH.
europepmc +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source
Comparison between bone lengthening using Ilizarov and lengthening over intramedullary nail
Background Leg length discrepancy alters the biomechanics of the pelvis, hip, knee, and walking. It can occur due to congenital or acquired causes. Limb length discrepancy is always managed by lengthening the shortened limb by distraction osteogenesis.
Mahmoud Khairy, Gratien Nzayikorera
openaire +1 more source
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez +8 more
wiley +1 more source
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Calcaneal Lengthening after Tarsal Bone Fusion for Massive Calcaneus Defect Reconstruction
Objectives Calcaneus defect remains challenging with limited strategies for reconstruction. Current methods, including graft transplantation, substitution, and distraction osteogenesis, showed limited advantages with certain shortcomings.
Rui Zhang +6 more
doaj +1 more source
When is it Safest to Remove Motorized Internal Lengthening Nails after Treatment Completion?
Background: Motorized intramedullary lengthening nails (MILNs) are a convenient option for limb lengthening. One MILN manufacturer states the nails should be removed 1 year following surgery.
Jidapa Wongcharoenwatana +4 more
doaj +1 more source
Experimental physeal distraction in immature sheep [PDF]
An experimental study on physeal distraction was carried out in the distal femur of 45 two-month-old lambs for the purpose of identifying the basic mechanism of lengthening as well as assessing growth cartilage viability after lengthening.
Cañadell, J.M. (J. M.) +1 more
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