Results 191 to 200 of about 19,638 (244)

REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma

Advanced Science, EarlyView.
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu, Shihui Shen, Dongxia Li, Peilin Shi, Jiaming Xu, Tongxin Lv, Yingying Du, Jingwei Zhang, Bo Yang, Hansen Chen, Zhuoya Peng, Wenjie Ren, Lu Zhang, Sheng Cheng, Tongjin Yin, Wencai Sheng, Lei Li, Juan Wu, Qingcheng Yang, Shuogui Xu, Wei Zheng   +20 more
wiley   +1 more source

[Biological aspects of bone lengthening].

Ortopediia travmatologiia i protezirovanie, 1985
V I, Stetsula, G I, Lavrishcheva, V P, Shtin, L N, Mikhaĭlova   +3 more
openaire   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Tibial lengthening in congenital pseudoarthrosis of the tibia: a scoping review. [PDF]

BMC Musculoskelet Disord
Kamath SK, Madegowda A, Baghel A, Singh KA, Shah HH.   +4 more
europepmc   +1 more source

A Rare Cosmetic Lengthening Complication Causing Precice Stryde Nail Failure: A Case Report. [PDF]

Sisli Etfal Hastan Tip Bul
Kanar M, Ipek E, Cakirturk S.
europepmc   +1 more source

Integration of Digital Smile Design Into Aesthetic and Functional Crown Lengthening: A Clinical Case Report. [PDF]

Cureus
Choudhary DS, Khiste SV.
europepmc   +1 more source

Acute shortening and re-lengthening (ASRL) procedure combined with RhBMP-2 to treat femur non-union with leg length discrepancy: a case report. [PDF]

Int J Surg Case Rep
Santoso A, Rahmi FN, Riyadli M, Warman FI, Brilianto BI, Anwar IB.   +5 more
europepmc   +1 more source

Ulnar lengthening for forearm deformities in hereditary multiple exostoses: a systematic review and meta-analysis (2015-2025). [PDF]

J Orthop Surg Res
Hamza MS.
europepmc   +1 more source

Radial head stabilization after ulnar lengthening in type IIB multiple hereditary exostoses: a pediatric case report using a limb reconstruction system and fixation button. [PDF]

Int J Surg Case Rep
Oppusunggu PP, Wienanda GK, Mitchel M, Gani KS, Kholinne E.   +4 more
europepmc   +1 more source