Results 31 to 40 of about 48,815 (294)

Emerging roles of telomeric chromatin alterations in cancer [PDF]

open access: yes, 2019
Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the ...
Biroccio, Annamaria   +2 more
core   +1 more source

Limb lengthening in pediatric patients with ollier's disease

open access: yesJournal of Limb Lengthening & Reconstruction, 2017
Background: Ollier's disease is a non-hereditary skeletal disorder. Orthopedic management of limb length discrepancy could be complex given the nature of bone pathology, the significant amount of length discrepancy and the difficulty to predict it.
Paige Goote   +6 more
doaj   +1 more source

Are Complications Associated With the Repiphysis(®) Expandable Distal Femoral Prosthesis Acceptable for Its Continued Use? [PDF]

open access: yes, 2015
BACKGROUND: Reconstruction of the distal femur after resection for malignant bone tumors in skeletally immature children is challenging. The use of megaprostheses has become increasingly popular in this patient group since the introduction of custom ...
Ali, N   +5 more
core   +1 more source

New bone formation accelerates during lower limb lengthening and deformity correction in children with Ollier’s disease

open access: yesJournal of Orthopaedics and Traumatology, 2023
Background Ollier’s disease can cause severe length discrepancy of the lower extremities and deformity in children. Osteotomy and limb lengthening with external fixation can correct the limb deformity.
Chunxing Wu   +5 more
doaj   +1 more source

Distraction Osteogenesis in the Combined and Sequential Use of Transosseous and Intramedullary Osteosynthesis: Experimental Study

open access: yesTravmatologiâ i Ortopediâ Rossii, 2021
Background. The methods of “lengthening over the nail” (LON) and the sequential use of the external fixation and nailing in the option “lengthening and then the nail” (LATN) are characterized by ignoring non-observance of the formulated by G.A.
E. A. Shchepkina   +6 more
doaj   +1 more source

Motorized Internal Lengthening of Long Bones: Residual Limb Lengthening

open access: yesTechniques in Orthopaedics, 2020
Distraction osteogenesis can be performed for transfemoral amputees using a motorized intramedullary limb lengthening nail (LLN) such as the 14×130 mm NuVasive Freedom nail. Despite being the shortest commercially available LLN, some patients have even shorter residual femurs, making it impossible to link the bone to the nail by the standard technique ...
Jason S. Hoellwarth   +3 more
openaire   +1 more source

PREDICTION OF THE DURATION OF DISTRACTION REGENERATED BONE MATURATION

open access: yesTravmatologiâ i Ortopediâ Rossii, 2012
Aim of the study the characteristics of changes of serum biochemical parameters in dogs with delayed maturation of the distraction regenerate after surgical lengthening the leg bones by Ilizarov.
N. V. Tushina   +3 more
doaj   +1 more source

Lower limb lengthening over an intramedullary nail: a long-term follow-up study of 28 cases

open access: yesJournal of Orthopaedics and Traumatology, 2019
Background Limb lengthening using an external fixator requires a long period of external fixation and may be associated with several complications such as axial deformity, fracture of the regenerated bone, and joint stiffness.
Pasquale Farsetti   +6 more
doaj   +1 more source

Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia

open access: yesChildren, 2021
Previous studies on lengthening for achondroplasia have reported bilateral extensive femoral lengthening followed by bilateral extensive tibial lengthening. To decrease trauma on soft tissues and joints, we propose bilateral simultaneous moderate femoral
Lior Shabtai   +5 more
doaj   +1 more source

Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. [PDF]

open access: yes, 2019
Denosumab has been used successfully to treat disease-associated osteoclast overactivity, including giant cell tumor of bone. Given its mechanism of action, denosumab is a potent potential treatment of other osteoclast bone dysplasias including central ...
Bernthal, Nicholas M   +8 more
core   +2 more sources

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